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Dupilumab
go.drugbank.com/drugs/DB12159ApprovedInvestigational[L7186,L7192,L41439] Dupilumab is currently under investigations for potential therapeutic use in diseases driven by allergic reactions or type 2 inflammation, such as pediatric atopic dermatitis, and … Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways.
Categories: Interleukin-4 Receptor alpha Antagonist, Interleukin 4 Receptor alpha AntagonistsProducts: DUPİXENT 200 mg/1,14 ml ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADET, DUPİXENT 300 MG/2ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADETNitroprusside
go.drugbank.com/drugs/DB00325ApprovedInvestigationalNitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). … Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Categories: Compounds used in a research, industrial, or household settingProducts: NITROPRUSIATO DE SODIO 50 MG/2 ML INYECTABLE, Nitroprussid-Natrium AFTPharm 50 mg/2 ml InfusionslösungLorazepam
go.drugbank.com/drugs/DB00186ApprovedInvestigationalLorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic.
Synonyms: o-Chloroxazepam, o-ChlorooxazepamProducts: ATIVAN 2 MG TABLETAS, LORAZEPAM 2 MG TABLETASMizagliflozin
go.drugbank.com/drugs/DB19036InvestigationalMizagliflozin is under investigation in clinical trial NCT05721729 (Effect of Mizagliflozin Repeat Dosing on Adverse Events and Postprandial Glucose Excursions).
Synonyms: 3-((3-(4-((3-(.beta.-d-glucopyranosyloxy)-5-(propan-2-yl)-1h-pyrazol-4-yl)methyl)-3-methylphenoxy)propyl)amino)-2,2-dimethylpropanamide, Propanamide, 3-((3-(4-((3-(.beta.-d-glucopyranosyloxy)-5-(1-methylethyl)-1h-pyrazol-4-yl)methyl)-3-methylphenoxy)propyl)amino)-2,2-dimethyl-Categories: Heterocyclic Compounds, 1-RingFulvestrant
go.drugbank.com/drugs/DB00947ApprovedInvestigationalWhile it is used as monotherapy for the treatment of breast cancers, it is also used in combination with [alpelisib] for the treatment of HR-positive, human epidermal growth factor receptor 2 (HER2)-negative … Fulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (7α,17β)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diolPitavastatin
go.drugbank.com/drugs/DB08860ApprovedInvestigationalMore specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid. … Prescribing of statin medications is considered standard practice following any cardiovascular events and for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: Trolise 2 mg Filmtabletten, LIVALO (TABLET 2 MG)Granisetron
go.drugbank.com/drugs/DB00889ApprovedInvestigationalA serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: Kytril 2 mg - Filmtabletten, KYTRIL 2 MG FİLM KAPLI TABLET, 5 ADETBudesonide
go.drugbank.com/drugs/DB01222ApprovedInvestigationalBudesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. … [L10598] It is also available in a combination product with [formoterol].[L10619]
Mixtures: POENA 2/400 MCG İNHALASYON İÇİN TOZ İÇEREN BLİSTER, 60 DOZ, POENA 2/400 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL ,60 KAPSÜLCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesRozanolixizumab
go.drugbank.com/drugs/DB14919ApprovedInvestigationalRozanolixizumab is a humanized high-affinity anti-human neonatal Fc receptor (FcRn) monoclonal antibody (IgG4P) targeting the immunoglobulin G (IgG). … [L47122] This is due to the efficacy demonstrated in the pivotal Phase 3 MycarinG study (NCT03971422).[L47122] Rozanolixizumab was also approved by the European Commission on January 5, 2024.[L50973]
Products: Rystiggo 280 mg/2 ml Enjeksiyonluk Çözelti, 1 adetMinnelide
go.drugbank.com/drugs/DB17309InvestigationalSynonyms: Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl-6a-(1-methylethyl)-6-((phosphonooxy)methoxy)-, sodium salt (1:2), (3bs,4as,5ar,6r,6as,7as,7bs,, 14-o-phosphonooxymethyltriptolide disodium salt