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MK-4721
go.drugbank.com/drugs/DB05933InvestigationalMK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell Antigen (PSCA), an antigen expressed at significant levels on tumor cells from the majority of patients
Digoxin Immune Fab (Ovine)
go.drugbank.com/drugs/DB00076ApprovedDigoxin Immune Fab is a sheep antibody (26-10) FAB fragment from sheep immunized with the digoxin derivative Digoxindicarboxymethylamine. It is used as an antidote for overdose of digoxin.
Dibutylphthalate
go.drugbank.com/drugs/DB13716ExperimentalCategories: Compounds used in a research, industrial, or household settingGallium citrate
go.drugbank.com/drugs/DB17893InvestigationalCategories: Compounds used in a research, industrial, or household settingAlvocidib
go.drugbank.com/drugs/DB03496InvestigationalIt works by inhibiting cyclin-dependent kinases, arresting cell division and causing apoptosis in non-small lung cancer cells. … Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer.
R-348
go.drugbank.com/drugs/DB06321InvestigationalSynonyms: 5-Fluoro-N-(4-methyl-3-propionylaminosulfonylphenyl)-N'-(4-(prop-2-ynyloxy)phenyl)-2,4-pyrimidinediamineNGX267
go.drugbank.com/drugs/DB05152InvestigationalNGX267 is a muscarinic agonist. It is developed for the treatment of Alzheimer’s disease and has shown the potential to both reduce symptoms and slow disease progression.
XL281
go.drugbank.com/drugs/DB05190InvestigationalXL281 is a specific inhibitor of RAF kinases, including the mutant form of B-RAF, which is activated in 60 percent of melanomas, 24-44 percent of thyroid cancers, and 9 percent of colon cancers. … Mutational activation of RAS occurs in about 30 percent of all human tumors, including non-small cell lung, pancreatic, and colon cancer.
Talniflumate
go.drugbank.com/drugs/DB09295InvestigationalIn addition, it is used in inflammatory conditions such as rheumatoid arthritis. … Phase I trials with talniflumate for the treatment of cystic fibrosis and COPD were completed in August 2001, and phase II trials were performed in Ireland for the treatment of cystic fibrosis but this
Barnidipine
go.drugbank.com/drugs/DB09227InvestigationalIt is available in modified-release oral tablets under the brand name Vasexten to be taken once daily in the morning. … Barnidipine has a gradual onset of action and is shown to be well tolerated in patients. It does not produce reflex tachycardia [A7842].