Search

Displaying results 4251 - 4260 of 10000 in total
  1. Drug

    Fenthion

    go.drugbank.com/drugs/DB11412
    ExperimentalVet approved

    Fenthion is listed as a restricted use compound by the United States Environmental Protection Agency due to its potential to cause cholinesterase inhibition in humans and animals. … Fenthion is an _organothiophosphate_ drug used as an insecticide, avicide, and acaricide.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: O,O-Dimethyl O-4-methylthio-m-tolyl phosphorothioate, O,O-Dimethyl O-[3-methyl-4-(methylsulfanyl)phenyl] thiophosphate
  2. Drug

    VIR201

    go.drugbank.com/drugs/DB05110
    Experimental

    is an experimental therapeutic vaccine currently in clinical trial. The aim of therapeutic vaccines is to augment the body's immune response to HIV and to delay or prevent progression to AIDS.

  3. Drug

    Indecainide

    go.drugbank.com/drugs/DB00192
    Approved

    Indecainide is a rarely used antidysrhythmic. … Indecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics

  4. Drug

    GnRH pharmaccine

    go.drugbank.com/drugs/DB05815
    Experimental

    The GnRH pharmaccine consists of synthetic peptides (constructed to "look like" GnRH), which are bound chemically to a carrier and suspended in a proprietary "delivery vehicle". … The pharmaccine is administered intramuscularly to the patient by injection and induces an immune response or production of antibodies in the patient, which neutralize GnRH thus removing it from circulation

  5. Drug

    CX501

    go.drugbank.com/drugs/DB05174
    Investigational

    It is developed by Cellerix and is in phase I of clinical trials. … Cx501 is used to treat epidermolysis bullosa (EB), a rare genetic condition which can lead to contraction of the joints, fusion of fingers and toes, contraction of the mouth membranes and narrowing of

  6. Drug

    DP-b99

    go.drugbank.com/drugs/DB05820
    Investigational

    DP-b99 is a newly developed lipophilic, cell permeable derivative of BAPTA (1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid), that is under development as a neuroprotectant for the potential treatment

  7. Pathway

    mTOR Signaling pathway

    smpdb.ca/view/SMP0535455
    Signaling

    as rapamycin and its analogs—has shown efficacy in cancer and aging models but may also perturb immune function and metabolic homeostasis. … the Ragulator–Rag GTPase complex to promote RagA/B‑GTP formation and mTORC1 lysosomal localization; and glutamine activates mTORC1 via a Rag-independent mechanism requiring the Arf1 GTPase (and Rab1A in

    Drugs: Arginine · L-Glutamine · Leucine · ATP · Magnesium cation · Zinc
    Enzymes: V-type proton ATPase subunit e 2
  8. Drug

    Pyridoxal phosphate

    go.drugbank.com/drugs/DB00114
    ApprovedInvestigationalNutraceutical

    This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. … During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).

    Mixtures: L-Methyl-B6-B12, Nutra-ZCategories: Vitamin B Complex, Heterocyclic Compounds, 1-Ring
  9. Drug

    ILY101

    go.drugbank.com/drugs/DB05059
    Investigational

    ILY101 is designed to allow for lower daily doses and improved patient acceptance and tolerability in comparison to other products in this class of drugs. … ILY101 is a metal-free, non-absorbed polymeric drug designed for the selective binding and removal of phosphate anions from the gastrointestinal tract.

  10. Drug

    Lobeline

    go.drugbank.com/drugs/DB05137
    Investigational

    It has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation. [PubChem] … An alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent.

    Categories: Heterocyclic Compounds, 1-Ring