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Displaying results 4271 - 4280 of 10000 in total
  1. Drug

    Cefixime

    go.drugbank.com/drugs/DB00671
    ApprovedInvestigational

    [A262995] Third-generation cephalosporins are often a first-line therapy against certain bacterial infections. … [A263026] However, cefixime is not recommended as a first-line of treatment for uncomplicated urogenital, anorectal, or pharyngeal gonorrhea because cefixime does not provide the same bactericidal effect

    Mixtures: MOLCEF PLUS 200 MG+62.5/5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN KURU TOZ, 100 ML, MOLCEF PLUS 100/62.5/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 MLCategories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Cefazolin

    go.drugbank.com/drugs/DB01327
    ApprovedInvestigational

    A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.

    Mixtures: CEFAMEZIN 250 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET, CEFAMEZIN 500 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADETCategories: Heterocyclic Compounds, 2-Ring
  3. Target

    Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase

    go.drugbank.com/bio_entities/BE0001689
    TargetMycobacterium tuberculosis

    Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. … Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions

    Polypeptides: Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolaseFunction: 4-hydroxy-4-methyl-2-oxoglutarate aldolase activity
  4. Drug

    Betiatide

    go.drugbank.com/drugs/DB14082
    Approved

    Products: Renoscint MAG3 1 mg Kit für ein radioaktives Arzneimittel, TECHNESCAN MAG3 KIT 1 mg/vial
  5. Drug

    Urea

    go.drugbank.com/drugs/DB03904
    ApprovedInvestigational

    A compound formed in the liver from ammonia produced by the deamination of amino acids. … It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.

    Mixtures: HYDROCORTISONE 1% ET UREA 5% CREAM, ROZA %1 + %2 KREM (30 G)Products: EXCİPİAL LİPO % 4 EMÜLSİYON, 200 ML, UBIT TABLET 100 MG
  6. Drug

    Esomeprazole

    go.drugbank.com/drugs/DB00736
    ApprovedInvestigational

    [A177571] Rapid discontinuation of PPIs such as esomeprazole may cause a rebound effect and a short term increase in hypersecretion. … Esomeprazole is the s-isomer of [DB00338], which is a racemate of the S- and R-enantiomer.

    Synonyms: (S)-omeprazole, (S)-(−)-omeprazoleInternational brands: ES-OD
  7. Drug

    Levetiracetam

    go.drugbank.com/drugs/DB01202
    ApprovedInvestigational

    make it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in drug interactions. … Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders.

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingProducts: KEPPRA 100 MG/ML LSG Z EIN, KEPPRA 100MG/ML LSG Z EIN
  8. Drug

    Cantuzumab mertansine

    go.drugbank.com/drugs/DB17239
    Experimental

    Synonyms: oxopropyl)maytansine (1:4), -oxopropyl)maytansine (1:4)
  9. Target

    Coagulation factor XIII A chain

    go.drugbank.com/bio_entities/BE0000004
    TargetEnzymeHumans

    Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot

    Polypeptides: Coagulation factor XIII A chainSynonyms: Transglutaminase A chain, Protein-glutamine gamma-glutamyltransferase A chain
  10. Target

    L-lactate dehydrogenase A chain

    go.drugbank.com/bio_entities/BE0000425
    TargetHumans

    Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+)

    Polypeptides: L-lactate dehydrogenase A chainSynonyms: LDH-A