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Aceprometazine
go.drugbank.com/drugs/DB01615ExperimentalAlthough not widely prescribed, it is used in combination with meprobamate for the treatment of sleep disorders in France under the trade name Mepronizine.
Brilaroxazine
go.drugbank.com/drugs/DB09226InvestigationalAs of May 2015, it is in phase III clinical trials for schizophrenia. … Brilaroxazine (RP5063) is an investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder.
Categories: Serotonin Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsIomeprol
go.drugbank.com/drugs/DB11705ApprovedInvestigationalIomeprol is a tri-iodinated, non-ionic radiographic contrast agent for intraarterial or intravenous use.
Cisapride
go.drugbank.com/drugs/DB00604ApprovedWithdrawnIn many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias.
Categories: Drugs for Functional Gastrointestinal Disorders, Serotonin Receptor AgonistsChlorothiazide
go.drugbank.com/drugs/DB00880ApprovedInvestigationalVet approvedA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
N-methylnicotinamide
go.drugbank.com/drugs/DB08840InvestigationalN-methylnicotinamide is an experimental drug with no approved indication or marketed formulation.
Categories: Preparations for Biliary Tract TherapyCorticotropin
go.drugbank.com/drugs/DB01285ApprovedInvestigationalVet approvedIt is an important player in the hypothalamic-pituitary-adrenal axis.
Categories: Corticosteroids for Systemic Use, Cytochrome P-450 SubstratesSermorelin
go.drugbank.com/drugs/DB00010ApprovedWithdrawnSermorelin acetate is the acetate salt of an amidated synthetic 29-amino acid peptide (GRF 1-29 NH 2 ) that corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing
Categories: Tests for Pituitary FunctionHuman Menstrual Blood-derived Stem Cells
go.drugbank.com/drugs/DB15738InvestigationalBecause this is a non-invasive way to obtain stem cells, it is simple and easy to obtain the stem cells with an absence of ethical issues that may come from obtaining stem cells of the embryonic kind.
Lumefantrine co-artemether
go.drugbank.com/drugs/DB13085ApprovedInvestigationalWithdrawnThe exact mechanism of action of lumefantrine is not well defined, but it is thought to inhibit -hematin formation, an important detoxification pathway for the parasite. … Lumefantrine Co-Artemether (Riamet) has been investigated for the treatment of Malaria, Malaria, Falciparum, Malaria in Pregnancy, Uncomplicated Malaria, and Uncomplicated Knowlesi Malaria.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates