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Methotrimeprazine
go.drugbank.com/drugs/DB01403ApprovedA phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSafflower oil
go.drugbank.com/drugs/DB09446ApprovedInvestigationalWithdrawnSafflower oil is approved for use as an indirect additive in food contact substances and is readily available as a food ingredient. … Extracted from the seeds of safflowers, safflower oil is a rich source of various saturated fatty acids, monounsaturated fatty acid (oleic acid) or essential n-6 polyunsaturated fatty acid (PUFA) linoleic
Desoxycorticosterone pivalate
go.drugbank.com/drugs/DB01134ExperimentalVet approvedFederal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.
Biomed 101
go.drugbank.com/drugs/DB05851InvestigationalBiomed 101 binds to the leukotriene B4 receptor, but does not affect interleukin-2 antitumor activity. … Biomed 101 is investigated for use/treatment in adverse effects (chemotherapy) and renal cell carcinoma. Biomed 101 is a solid.
Olesoxime
go.drugbank.com/drugs/DB05185InvestigationalFor example, it has demonstrated the ability to prevent neurodegeneration, enhance nerve function and accelerate neuroregeneration following nerve trauma.[A3282,A253233]
MB-07803
go.drugbank.com/drugs/DB05053InvestigationalMB07803 is a second generation gluconeogenesis inhibitor for the treatment of type 2 diabetes. It is designed to block the metabolic pathway in the liver that is responsible for producing glucose.
beta-Hydroxybutyric acid
go.drugbank.com/drugs/DB16506Investigational(completed for type 1 diabetes), and NCT05581043 (completed for type 2 diabetes). … Beta-hydroxybutyrate is being studied in around 230 clinical trials, including NCT06351124 (recruiting for Crohn's disease), NCT05584371 (recruiting for safety and tolerability of exogenous ketosis), NCT04656236
Categories: Experimental Unapproved Treatments for COVID-19N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine
go.drugbank.com/drugs/DB13948ExperimentalIt has been tested with regard to the head-twitch-response (HTR) model of 5-HT2A activity and effects on locomotion [L1148]. It was discovered in 2014 at the University of Copenhagen.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeMitoquinone
go.drugbank.com/drugs/DB05063InvestigationalMitochondrial dysfunction also has been shown to represent an early critical event in the pathogenesis of the sporadic form of Parkinson's disease. … -- where they accumulate up to a thousand fold.
Thiethylperazine
go.drugbank.com/drugs/DB00372ApprovedInvestigationalWithdrawnThis piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
Categories: Antihistamines for Systemic Use