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Displaying results 421 - 430 of 10000 in total
  1. Pathway

    Vitamin A Deficiency

    smpdb.ca/view/SMP0125788
    Disease

    Vitamin A deficiency can be caused by many causes. A defect in the BCMO1 gene which codes for beta,beta-carotene 15,15’-monooxygenase is one of them. Beta,beta-carotene 15,15’-monooxygenase catalyzes the chemical reaction where the two s...

    Drugs: NADH · Vitamin A · Alitretinoin · Tretinoin · Iron · Zinc +2 more
  2. Pathway

    Vitamin A Deficiency

    smpdb.ca/view/SMP0000336
    Disease

    Vitamin A deficiency can be caused by many causes. A defect in the BCMO1 gene which codes for beta,beta-carotene 15,15’-monooxygenase is one of them. Beta,beta-carotene 15,15’-monooxygenase catalyzes the chemical reaction where the two s...

    Drugs: NADH · Vitamin A · Alitretinoin · Tretinoin · Iron · Zinc +2 more
  3. Pathway

    Retinol Metabolism

    smpdb.ca/view/SMP0000074
    Metabolic

    This conversion is caused by the absorption of light into the retinal portion of the protein complex, which then isomerizes, forcing the protein to change shape to accomodate this. … Finally, in the endoplasmic reticulum, all-trans-retinoic acid can undergo epoxidation to form all-trans-5,6-epoxyretinoic acid by interaction with a complex of cytochrome P450 proteins, or hydroxylated

    Drugs: NADH · Vitamin A · Alitretinoin · Tretinoin · Iron · Zinc +2 more
  4. Drug

    Trospium

    go.drugbank.com/drugs/DB00209
    ApprovedInvestigational

    [L6208] An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination. … [L6208] Trospium is manufactured by _Indevus Pharmaceutical Inc._ and was granted FDA approval in 2007.[L6211]

    Products: Trospium Chloride ER
  5. Drug

    Niacin

    go.drugbank.com/drugs/DB00627
    ApprovedInvestigationalNutraceutical

    Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.

    Mixtures: Pro Enz Tab, Ni-C-E-LE PlusCategories: Vitamin B Complex
  6. Drug

    Darifenacin

    go.drugbank.com/drugs/DB00496
    ApprovedInvestigational

    This block reduces the urgency to urinate and so it should not be used in people with urinary retention. … It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.

    Products: DARUCIL® ER 15 MG
  7. Drug

    Flecainide

    go.drugbank.com/drugs/DB01195
    ApprovedInvestigationalWithdrawn

    [A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. … [L8878,L5056] Flecainide was granted FDA approval on 31 October 1985.[L8875]

    Synonyms: N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamideProducts: FLECAINIDE EG
  8. Drug

    Trimipramine

    go.drugbank.com/drugs/DB00726
    ApprovedInvestigational

    Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.

    Synonyms: 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamineProducts: TRIMINEURIN 40 MG/ML Z EIN
  9. Drug

    Cyclobenzaprine

    go.drugbank.com/drugs/DB00924
    ApprovedInvestigational

    Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been available for human use since 1977. … [A185039,A184982] Since its approval, it has remained relatively popular as an adjunctive, short-term treatment for acute skeletal muscle spasms secondary to musculoskeletal injury.

    Mixtures: RODALGIN COMPLEX TABLETASSynonyms: N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Δ5,γ-propylamine
  10. Drug

    Mometasone

    go.drugbank.com/drugs/DB00764
    ApprovedInvestigational

    Mometasone is a corticosteroid not currently used in medical products. [Mometasone furoate] however, is still in use.

    Products: MOMETASONE EG