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Telotristat ethyl
go.drugbank.com/drugs/DB12095Approved[A252937] The first line treatment of carcinoid syndrome diarrhea is SSA, but symptoms still reoccur over the course of the disease.[A252937] … [L43342] It was previously referred to as telotristat etiprate, the hippurate salt form; however, the FDA recommends the use of the name of the neutral form rather than that of the salt.
Povidone-iodine
go.drugbank.com/drugs/DB06812ApprovedInvestigationalPovidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. … During in vitro testing to demonstrate anti-bacterial activity it was found that the complex was less toxic in mice than tincture of iodine.
Mixtures: Point Of Care Kit KM, Point Of Care LM 2.2Categories: Compounds used in a research, industrial, or household settingGentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approved[A234349] It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability. … [A233325,A234359,A234364] There is the added benefit of synergy when gentamicin is co-administered with other antibacterials such as beta-lactams.
International brands: G-MycinMixtures: GENTAMICINA E BETAMETASONE SUN, Gentamicin Sulfate In Nacl O.9% InjSelenic acid
go.drugbank.com/drugs/DB11068ApprovedIt may be found in over-the-counter daily dietary supplements as a source of [DB11135], an essential trace mineral for human health.
Mixtures: Vp-heme Ob, Cavan Heme OBCategories: Compounds used in a research, industrial, or household settingTapentadol
go.drugbank.com/drugs/DB06204ApprovedInvestigational[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011. … [L47291] Used in the management of pain, tapentadol is typically reserved for patients who have limited alternative treatment options.
Categories: Combined Inhibitors of Serotonin/Norepinephrine Reuptake, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: PALEXIS® 75 MG, PALEXIS ® 50 MG.Naloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approvedThere are over-the-counter nasal sprays available. When injected intramuscularly (IM), naloxone acts within three to five minutes. … ] or [cocaine], or benzodiazepines like [lorazepam] or [diazepam].
Mixtures: OXYCODON COMP EVER 10/5MG, OXYCODON COMP EVER 10/5MGCategories: Heterocyclic Compounds with 4 or More RingsValproate bismuth
go.drugbank.com/drugs/DB13910ApprovedValproate bismuth is available in Canada in the over-the-counter medication Neo-Laryngobis.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeEntrectinib
go.drugbank.com/drugs/DB11986ApprovedInvestigationalThis therapy offers benefit over similar ALK inhibitors such as [alectinib], [ceritinib], and [lorlatinib] due to a wider range of targets.[A183929] … [L8207] Entrectinib's approved use is meant as a last line of therapy due to its accelerated approval based on early trial data.
Products: R O Z Lytrek, ROZLYTREK 200 MG SERT KAPSÜL, 90 ADETCiprofloxacin
go.drugbank.com/drugs/DB00537ApprovedInvestigational[A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections. … [L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.[L6463]
Mixtures: OQ-CORT®, ORNISASIN 500 MG/500 MG FILM TABLET, 10 ADETCategories: Metabolic Side Effects of Drugs and SubstancesRanitidine
go.drugbank.com/drugs/DB00863ApprovedWithdrawn[L10818,F4253] The prevalence of GERD is thought to be 10-20% in western countries. … This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion.
Products: RANITIDINA SUN, Nu-ranit Tab 150mg