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High mobility group protein HMG-I/HMG-Y
go.drugbank.com/bio_entities/BE0012648TargetHumansHMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA.
Polypeptides: High mobility group protein HMG-I/HMG-YSynonyms: HMG-I(Y)Human thrombin
go.drugbank.com/drugs/DB11571ApprovedInvestigationalThrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin. … Furthermore, human thrombin is manufactured by chromatographic purification of prothrombin from cryo-poor plasma followed by activation with calcium chloride [FDA Label].
Mixtures: EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/ml, EVICEL® SELLANTE DE FIBRINA HUMANAProducts: THROMBIRAAS1000 UISymptomatic for no more than 48 hours.
go.drugbank.com/conditions/DBCOND0116964Drugs: OseltamivirSynonyms: Symptomatic for no more than 48 hours, Symptomatic for no more than 48 hours.No disease progression during platinum-based chemotherapy
go.drugbank.com/conditions/DBCOND0173076Synonyms: No disease progression during platinum-based chemotherapyMoroctocog alfa
go.drugbank.com/drugs/DB13999ApprovedMoroctocog alfa is identical in sequence to endogenously produced Factor VIII, but does not contain the B-domain, which has no known biological function. … Bleeding can range in severity from minor concerns, such as nosebleeds, to more serious events such as hemorrhaging in the joints, brain, or digestive tract [A32280].
Synonyms: B-domain deleted recombinant factor VIII, Human factor VIII, recombinant B-domain deletedProducts: XYNTHA® 2000 UI, XYNTHA® 250 UI POLVO LIOFILIZADO PARA SOLUCION INYECTABLETuroctocog alfa
go.drugbank.com/drugs/DB09109Approved[A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] … Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally
Products: NOVOEIGHT®1000 UI POLVO Y SOLVENTE PARA SOLUCIÓN INYECTABLE, NOVOEIGHT® 250 UI POLVO Y SOLVENTE PARA SOLUCIÓN INYECTABLEDronabinol
go.drugbank.com/drugs/DB00470ApprovedIllicitInvestigationalCB2 receptors are mainly located in the peripheral nervous system and can be found on lymphoid tissue where they are involved in regulation of immune function [A32676]. … Due to its evidence as an appetite stimulant and an anti-nauseant, Dronabinol is approved for use in anorexia associated with weight loss in patients with AIDS and for the treatment of nausea and vomiting
Synonyms: 3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,d)pyran-1-ol, 1-trans-delta-9-TetrahydrocannabinolCategories: Analgesics, Non-Narcotic, P-glycoprotein inhibitorsInfliximab
go.drugbank.com/drugs/DB00065ApprovedInvestigationalInfliximab was first approved by the FDA in 1998 under the market name Remicade as an intravenous injection. … There are currently two biosilimars of infliximab available in the US market that demonstrate a high degree of similarity to the reference product, Remicade.
Synonyms: IMMUNOGLOBULIN G (HUMAN-MOUSE MONOCLONAL CA2 HEAVY CHAIN ANTI-HUMAN TUMOR NECROSIS FACTOR), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL CA2 LIGHT CHAIN, DIMERProducts: INFLECTRA 100MG PLV F E KO, REMICADE 100MG PULV F E KOLimited or no alternative treatment options
go.drugbank.com/conditions/DBCOND0156255Drugs: Avibactam · Aztreonam · Metronidazole · Rezafungin · Sulopenem etzadroxil · Tebipenem pivoxil +2 moreSynonyms: Limited or no alternative treatment optionsNo history of Factor IX inhibitors
go.drugbank.com/conditions/DBCOND0155586Synonyms: No history of Factor IX inhibitors