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Phenazopyridine
go.drugbank.com/drugs/DB01438ApprovedInvestigationalPhenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug ...
Products: ALMAX NXIndium In-111 satumomab pendetide
go.drugbank.com/drugs/DB00057ApprovedWithdrawnSatumomab Pendetide (trade name: OncoScint®) is no longer commercially available. … Tumor associated glycoprotein (TAG) 72 (B72.3) monoclonal antibody conjugated with Indium 111 for radioimaging colon tumors.
Norfloxacin
go.drugbank.com/drugs/DB01059ApprovedInvestigationalA synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP3A InhibitorsProducts: N-FLOXA 200, N-FLOXA 400Candesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalCandesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite,...
Mixtures: CANDESARTAN COMP PU 8/12.5, CANDESARTAN COMP PU 8/12.5Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesIndigofera tinctoria leaf
go.drugbank.com/drugs/DB14314InvestigationalIndigofera tinctoria leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Qing Dai (Indigofera Tinctoria)Fluconazole
go.drugbank.com/drugs/DB00196ApprovedInvestigationalFluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifun...
Mixtures: Canesoral Combi 1 DayCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsPregabalin
go.drugbank.com/drugs/DB00230ApprovedInvestigationalPregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter.
Products: Nb-pregabalin, PG-LIN 75 (Pregabalin Capsules 75 mg)Nicotine
go.drugbank.com/drugs/DB00184ApprovedInvestigationalNicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of it...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersSynonyms: 3-(N-methylpyrollidino)pyridine, 3-(2-(N-methylpyrrolidinyl))pyridinePrednisolone
go.drugbank.com/drugs/DB00860ApprovedInvestigationalVet approvedPrednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: Predniso(lo)nePembrolizumab
go.drugbank.com/drugs/DB09037ApprovedInvestigationalPembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. … It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors