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Bendamustine
go.drugbank.com/drugs/DB06769ApprovedInvestigationalThrough this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death. … Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: BENDAMUSTINA DR. REDDY'S, GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLEBeta carotene
go.drugbank.com/drugs/DB06755ApprovedNutraceutical[T158] Under the FDA, beta-carotene is considered as a generally recognized as safe substance (GRAS).[L2191] … [T162] It is the most abundant form of carotenoid and it is a precursor of the vitamin A. Beta-carotene is composed of two retinyl groups.
Mixtures: Doctor's Choice Brand for Men, Somavit Brand Vitamins and Minerals ComplexCategories: Vitamin ACyanocobalamin
go.drugbank.com/drugs/DB00115ApprovedInvestigationalNutraceuticalThis drug was initially approved by the FDA in 1942 [FDA label]. … This vitamin is produced naturally by bacteria [A175276], and is necessary for DNA synthesis and cellular energy production.
Mixtures: Daily Energy Brand B-complex, Doctor's Choice Brand for MenUrea
go.drugbank.com/drugs/DB03904ApprovedInvestigationalA compound formed in the liver from ammonia produced by the deamination of amino acids.
Mixtures: Dr. Scholl's Cracked Heel Relief Cream, Urea 40 Plus SAProducts: Avenaster Fungal Nail Care Duo Set (day), EUREA CREAMSotrovimab
go.drugbank.com/drugs/DB16355ApprovedInvestigational[L41369] Sotrovimab was granted marketing authorization in the European Union in December 2021 under the brand name Xevudy.[L39625,L39620] … [L34425, L34430, L34440] However, in April 2022, the FDA removed the EUA for sotrovimab due to the rising COVID-19 cases caused by the Omicron BA.2 sub-variant, where the drug is ineffective.
Vitamin A
go.drugbank.com/drugs/DB00162ApprovedInvestigationalNutraceuticalVet approvedDietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.
Synonyms: Vitamin A Alcohol, all-trans-vitamin A alcoholInternational brands: Chocola AOfloxacin
go.drugbank.com/drugs/DB01165ApprovedInvestigationalA synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Synonyms: 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acidProducts: FLOXSTAT (R)TABLETAS DE 200 MGTicagrelor
go.drugbank.com/drugs/DB08816ApprovedInvestigational[L14207] Ticagrelor was granted FDA approval on 20 July 2011.[L14201] … [A2903] Unlike [clopidogrel], ticagrelor is not a prodrug.[A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU,[L14207].
Synonyms: (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diolProducts: Na, TICAGRELOR DR. REDDY'SGlucosamine
go.drugbank.com/drugs/DB01296ApprovedOsteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. … [A231894,A232289] It is currently not approved as a prescription product by the FDA, but is widely available over the counter.
Synonyms: D-Glucosamine, 2-amino-2-deoxy-D-glucoseMixtures: GLUCONITRIN D, GLUCONITRIN DGrape seed oil
go.drugbank.com/drugs/DB14323InvestigationalGrape seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: European Grape Seed Oil