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Displaying results 4291 - 4300 of 10000 in total
  1. Drug

    Zinc ascorbate

    go.drugbank.com/drugs/DB14485
    ApprovedNutraceutical

    Categories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  2. Drug

    Evocalcet

    go.drugbank.com/drugs/DB12388
    Investigational

    Evocalcet has been used in trials studying the treatment of Hyperparathyroidism and Secondary Hyperparathyroidism.

    Categories: Sex Hormones and Insulins
  3. Drug

    Thalidomide

    go.drugbank.com/drugs/DB01041
    ApprovedInvestigationalWithdrawn

    A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects.

  4. Drug

    Gestodene

    go.drugbank.com/drugs/DB06730
    Investigational

    Gestodene is a progestogen hormonal contraceptive.

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  5. Drug

    Rucaparib

    go.drugbank.com/drugs/DB12332
    ApprovedInvestigational

    Rucaparib is an anticancer drug and poly (ADP-ribose) polymerase (PARP) inhibitor. PARP is an enzyme that plays an essential role in DNA repair. … [L42185] It is currently used to treat recurrent ovarian and prostate cancer in adults.[L42155,L42185].

  6. Target

    Proteasome subunit beta type-8

    go.drugbank.com/bio_entities/BE0004739
    TargetHumans

    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic

    Synonyms: Multicatalytic endopeptidase complex subunit C13
  7. Drug

    Sugammadex

    go.drugbank.com/drugs/DB06206
    ApprovedInvestigational

    Sugammadex (brand name Bridion) is marketed by Merck Sharp and Dohme, and was approved by the United States FDA on December 15, 2015. … Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery.

  8. Target

    Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial

    go.drugbank.com/bio_entities/BE0002252
    TargetHumans

    Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to

    Synonyms: Succinate dehydrogenase complex subunit D
  9. Target

    Proteasome subunit alpha type-1

    go.drugbank.com/bio_entities/BE0003910
    TargetHumans

    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)

    Synonyms: Multicatalytic endopeptidase complex subunit C2
  10. Drug

    Smallpox (Vaccinia) Vaccine, Live

    go.drugbank.com/drugs/DB14711
    ApprovedInvestigational

    The New York City Board of Health strain of _Vaccinia_ is a viral strain used as a component of some smallpox vaccinations.

    Categories: Complex Mixtures