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Displaying results 4301 - 4310 of 10000 in total
  1. Target

    Inositol-trisphosphate 3-kinase A

    go.drugbank.com/bio_entities/BE0001627
    TargetHumans

    Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis

    Polypeptides: Inositol-trisphosphate 3-kinase ASynonyms: IP3K A, IP3 3-kinase A
  2. Target

    Complement C1q subcomponent subunit A

    go.drugbank.com/bio_entities/BE0002094
    TargetHumans

    The C1Q subcomplex is activated by a hexamer of IgG complexed with antigens, while it is activated by a pentameric IgM (PubMed:19706439, PubMed:24626930, PubMed:29449492). … Core component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens

    Polypeptides: Complement C1q subcomponent subunit A
  3. Target

    Amine oxidase [flavin-containing] A

    go.drugbank.com/bio_entities/BE0002198
    TargetEnzymeHumans

    Also catalyzes the oxidative deamination of kynuramine to 3-(2-aminophenyl)-3-oxopropanal that can spontaneously condense to 4-hydroxyquinoline (By similarity)

    Polypeptides: Amine oxidase [flavin-containing] ASynonyms: MAO-A, Monoamine oxidase type A
  4. Target

    Endo-1,4-beta-xylanase A

    go.drugbank.com/bio_entities/BE0002739
    TargetClostridium stercorarium

    Endoxylanase that degrades arabinoxylan and glucuronoxylan to xylobiose and xylotriose (in vitro).

    Polypeptides: Endo-1,4-beta-xylanase ASynonyms: 1,4-beta-D-xylan xylanohydrolase A
  5. Target

    Endo-1,4-beta-xylanase A

    go.drugbank.com/bio_entities/BE0003244
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: Endo-1,4-beta-xylanase ASynonyms: Xylanase A, 1,4-beta-D-xylan xylanohydrolase A
  6. Target

    Ephrin type-A receptor 1

    go.drugbank.com/bio_entities/BE0009436
    TargetHumans

    Also plays a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis … Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand.

    Polypeptides: Ephrin type-A receptor 1
  7. Target

    Ephrin type-A receptor 8

    go.drugbank.com/bio_entities/BE0009440
    TargetHumans

    During development of the nervous system also plays a role in axon guidance. … The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation.

    Polypeptides: Ephrin type-A receptor 8
  8. Indication

    Chronic hepatitis C genotype 4 without cirrhosis

    go.drugbank.com/conditions/DBCOND0124148
    Drugs: Ombitasvir · Paritaprevir
    Synonyms: Chronic hepatitis C genotype 4 without cirrhosis, Without cirrhosis Chronic hepatitis C genotype 4
  9. Drug

    Iopamidol

    go.drugbank.com/drugs/DB08947
    ApprovedInvestigational

    Iopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties.

    Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast ActivityProducts: PAMIRAY 370 ENJ. 50 ML 0,755 MG FLAKON, 1 ADET, PAMIRAY 370 ENJ. 100 ML 0,755 MG FLAKON, 1 ADET
  10. Target

    Neutral amino acid transporter A

    go.drugbank.com/bio_entities/BE0000480
    TargetHumans

    Involved in homeostasis of D-serine, a coagonist of synaptic NMDA receptors. … Displays sodium- and amino acid-dependent but uncoupled channel-like anion conductance with a preference SCN(-) > NO3(-) > I(-) > Cl(-) (PubMed:8910405)

    Polypeptides: Neutral amino acid transporter ASynonyms: Solute carrier family 1 member 4