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Displaying results 4311 - 4320 of 10000 in total
  1. Target

    Melanoma-associated antigen 4

    go.drugbank.com/bio_entities/BE0010534
    TargetHumans

    Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase (PubMed:22842486). Also negatively regulates p53-mediated apoptosis (PubMed:22842486)

    Polypeptides: Melanoma-associated antigen 4Synonyms: MAGE-4 antigen
  2. Target

    Alpha-(1,3)-fucosyltransferase 4

    go.drugbank.com/bio_entities/BE0012925
    EnzymeHumans

    Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked … Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins (PubMed:1716630, PubMed

    Polypeptides: Alpha-(1,3)-fucosyltransferase 4Synonyms: Fucosyltransferase 4, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase
  3. Target

    Double homeobox protein 4

    go.drugbank.com/bio_entities/BE0020504
    TargetHumans

    Transcription factor that is selectively and transiently expressed in cleavage-stage embryos (PubMed:28459457). Binds to double-stranded DNA elements with the consensus sequence 5'-TAATCTAATCA-3' (PubMed:28459454, PubMed:28459457, PubMed...

    Polypeptides: Double homeobox protein 4
  4. Drug

    Gabapentin

    go.drugbank.com/drugs/DB00996
    ApprovedInvestigational

    Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA]) that was first approved for use in the United States in 1993. … [L8717] It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic pain.

    Mixtures: Innoprax-5, GAVINDO NSynonyms: 1-(Aminomethyl)cyclohexaneacetic acid
  5. Drug

    Etevritamab

    go.drugbank.com/drugs/DB17211
    Investigational

    Synonyms: (CD3 EPSILON, LEU-4)), MONOCLONAL ANTIBODY SINGLE, Anti-egfrviii/cd3 bite antibody amg 596
  6. Drug

    Bicalutamide

    go.drugbank.com/drugs/DB01128
    ApprovedInvestigational

    It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers. Bicalutamide binds to the androgen receptor.

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsProducts: CASODEX® 150 MG, BICAN ® 50 MG TABLETAS
  7. Target

    Potassium channel subfamily K member 6

    go.drugbank.com/bio_entities/BE0000680
    TargetHumans

    K(+) channel that conducts outward rectifying currents at the membranes of the endolysosomal system (PubMed:10887187, PubMed:28381826, PubMed:40343992, PubMed:41617707). Active in lysosomes where it regulates lysosome numbers and size (P...

    Polypeptides: Potassium channel subfamily K member 6
  8. Target

    Putative mannose-6-phosphate isomerase YvyI

    go.drugbank.com/bio_entities/BE0002646
    TargetBacillus subtilis (strain 168)

    Polypeptides: Putative mannose-6-phosphate isomerase YvyIFunction: mannose-6-phosphate isomerase activity
  9. Target

    Aminoglycoside N(6')-acetyltransferase type 1

    go.drugbank.com/bio_entities/BE0002677
    TargetEnzymeSalmonella enteritidis

    Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring including amikacin, tobramycin

    Polypeptides: Aminoglycoside N(6')-acetyltransferase type 1Synonyms: AAC(6')-Iy
  10. Target

    Ribosomal protein S6 kinase alpha-6

    go.drugbank.com/bio_entities/BE0009380
    TargetHumans

    Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis

    Polypeptides: Ribosomal protein S6 kinase alpha-6Synonyms: RSK-4, Ribosomal S6 kinase 4