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Displaying results 4311 - 4320 of 10000 in total
  1. Drug

    Azelaic acid

    go.drugbank.com/drugs/DB00548
    ApprovedInvestigational

    It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. … Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley.

    Categories: Skin and Mucous Membrane Agents
  2. Drug

    Procarbazine

    go.drugbank.com/drugs/DB01168
    ApprovedInvestigational

    An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.

    Categories: Benzamides and benzamide derivatives, Antineoplastic and Immunomodulating Agents
  3. Drug

    Demecarium

    go.drugbank.com/drugs/DB00944
    Approved

    Demecarium inactivates both pseudocholinesterase and acetylcholinesterase. In the eye, this causes constriction of the iris sphincter muscle (causing miosis) and the ciliary muscle. … Demecarium is an indirect-acting parasympathomimetic agent that is used to treat glaucoma. It is a cholinesterase inhibitor or an anticholinesterase.

    Categories: Antiglaucoma Preparations and Miotics
  4. Drug

    Epicept NP-1

    go.drugbank.com/drugs/DB05492
    Investigational

    The peripheral nervous system includes nerves that run from the brain and spinal cord to the rest of the body. … EpiCept NP-1 Cream is a patented formulation containing two FDA-approved drugs, amitriptyline (a widely-used antidepressant) and ketamine (an NMDA antagonist that is used as an anesthetic).

  5. Drug

    Isoflavone

    go.drugbank.com/drugs/DB12007
    ApprovedInvestigationalWithdrawn

    , type II diabetes mellitus, and breast and prostate cancer [A33099]. … The main soy isoflavones are mostly present in glycosylated forms and include [DB01645], [DB13182], and glycitein, which accounts for approximately 50%, 40%, and 10%, respectively, of the total soybean

  6. Drug

    Ribociclib

    go.drugbank.com/drugs/DB11730
    ApprovedInvestigational

    These proteins, when over-activated, can enable cancer cells to grow and divide too quickly. Ribociclib was approved by the FDA in March 2017 under the brand name Kisqali. … Ribociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6).

    Categories: Antineoplastic and Immunomodulating Agents
  7. Drug

    Chlorotoxin I-131

    go.drugbank.com/drugs/DB05462
    Investigational

    It is a synthetic version of a neurotoxin isolated from the venom of the Giant Yellow Israeli scorpion Leiurus quinquestriatus. … Chlorotoxin is a small 36-amino-acid peptide that selectively binds to glioma cells but not normal brain parenchyma.

  8. Drug

    MK-8245

    go.drugbank.com/drugs/DB13024
    Investigational

    MK-8245 has been used in trials studying the treatment of Type 2 Diabetes Mellitus.

  9. Drug

    Toluene

    go.drugbank.com/drugs/DB11558
    InvestigationalVet approved

    It is a mono-substituted benzene derivative used in veterinary medicine as a treatment for various parasites in dogs and cats.

  10. Drug

    Larazotide

    go.drugbank.com/drugs/DB05645
    Investigational

    An octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease.

    Categories: Amino Acids, Peptides, and Proteins