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Displaying results 4351 - 4360 of 8010 in total
  1. Drug

    Stavudine

    go.drugbank.com/drugs/DB00649
    ApprovedInvestigational

    A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  2. Drug

    Aminopterin

    go.drugbank.com/drugs/DB08878
    ApprovedWithdrawn

    In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment of psoriasis.

  3. Drug

    Hexobendine

    go.drugbank.com/drugs/DB13265
    Approved

    It has not been approved in the United States or the United Kingdom, but has been used widely in Austria and Germany [T478].

  4. Drug

    Ulobetasol

    go.drugbank.com/drugs/DB00596
    Approved

    Ulobetasol is a highly potent corticosteroid. It is structurally related to clobetasol. Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses. Ulobetasol was...

    Categories: Antipsoriatics for Topical Use
  5. Drug

    Phenolsulfonphthalein

    go.drugbank.com/drugs/DB13212
    Experimental

    Phenolsulfonphthalein is being investigated for use clinically due to its weak estrogen mimicking actions [A174964]. … Phenolsulfonphthalein or otherwise called phenol red is a pH indicator commonly used in cell biology laboratories.

    Categories: Tests for Renal Function and Ureteral Injuries, Compounds used in a research, industrial, or household setting
  6. Drug

    Paromomycin

    go.drugbank.com/drugs/DB01421
    ApprovedInvestigational

    An oligosaccharide antibiotic produced by various streptomyces. [PubChem]

  7. Drug

    humanized SMART Anti-IL-12 Antibody

    go.drugbank.com/drugs/DB05848
    Experimental

    SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La Roche Inc … The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases.

  8. Drug

    Zanamivir

    go.drugbank.com/drugs/DB00558
    ApprovedInvestigational

    A guanido-neuraminic acid that is used to inhibit neuraminidase.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  9. Drug

    Lomustine

    go.drugbank.com/drugs/DB01206
    ApprovedInvestigational

    An alkylating agent of value against both hematologic malignancies and solid tumors.

  10. Drug

    VA-MENGOC-BC®

    go.drugbank.com/drugs/DB15800
    Experimental

    As there already exists a polysaccharide-based vaccine against meningococcal disease originating from serogroups A,C,W135, and Y, this vaccine was created for use against serogroups B and C. … As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials.