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Neuropeptide Y receptor type 4
go.drugbank.com/bio_entities/BE0002418TargetHumansG protein-coupled receptor for PPY/pancreatic polypeptide/PP, NPY/neuropeptide Y and PYY/peptide YY that is negatively coupled to cAMP (PubMed:7493937, PubMed:7592911). The rank order of affinity for these polypeptides and their derivati...
Polypeptides: Neuropeptide Y receptor type 4DNA topoisomerase 4 subunit A
go.drugbank.com/bio_entities/BE0003726TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA (PubMed:17375187, PubMed:20596531). Performs the decatenation events required during the replication of a circular DNA molecule.
Polypeptides: DNA topoisomerase 4 subunit AProteasome subunit alpha type-4
go.drugbank.com/bio_entities/BE0003913TargetHumansComponent of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associat...
Polypeptides: Proteasome subunit alpha type-4Hepatocyte nuclear factor 4-alpha
go.drugbank.com/bio_entities/BE0004019TargetHumansTranscriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes (PubMed:30597922)...
Polypeptides: Hepatocyte nuclear factor 4-alphaSynonyms: HNF-4-alpha, Transcription factor HNF-4Ephrin type-A receptor 4
go.drugbank.com/bio_entities/BE0009438TargetHumansReceptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referr...
Polypeptides: Ephrin type-A receptor 4Mitogen-activated protein kinase 4
go.drugbank.com/bio_entities/BE0009476TargetHumansThe precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated
Polypeptides: Mitogen-activated protein kinase 4Synonyms: ERK-4, MAPK 4DNA polymerase delta subunit 4
go.drugbank.com/bio_entities/BE0020436TargetHumansAs a component of the tetrameric DNA polymerase delta complex (Pol-delta4), plays a role in high fidelity genome replication and repair. Within this complex, increases the rate of DNA synthesis and decreases fidelity by regulating POLD1 ...
Polypeptides: DNA polymerase delta subunit 4Cardiolipin Biosynthesis CL(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
smpdb.ca/view/SMP0029737MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Cardiolipin Biosynthesis CL(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:4(5Z,8Z,11Z,14Z))
smpdb.ca/view/SMP0030221MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Cardiolipin Biosynthesis CL(18:4(6Z,9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
smpdb.ca/view/SMP0220243MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...