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ADP-ribosylation factor 4
go.drugbank.com/bio_entities/BE0003277TargetHumansGTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Part...
Polypeptides: ADP-ribosylation factor 4Microtubule-associated protein 4
go.drugbank.com/bio_entities/BE0003475TargetHumansNon-neuronal microtubule-associated protein. Promotes microtubule assembly
Polypeptides: Microtubule-associated protein 4Synonyms: MAP-4Disks large homolog 4
go.drugbank.com/bio_entities/BE0004524TargetHumansPostsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins.
Polypeptides: Disks large homolog 4Tropomyosin alpha-4 chain
go.drugbank.com/bio_entities/BE0009039TargetHumansPlays a role in platelet biogenesis … Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.
Polypeptides: Tropomyosin alpha-4 chainSynonyms: Tropomyosin-4Sodium/glucose cotransporter 4
go.drugbank.com/bio_entities/BE0014888TransporterHumansExclusively recognizes sugar substrates having a pyranose ring with an axial hydroxyl group on carbon 2 … Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump.
Polypeptides: Sodium/glucose cotransporter 4Synonyms: Na(+)/glucose cotransporter 4Chondroitin sulfate proteoglycan 4
go.drugbank.com/bio_entities/BE0015621TargetHumansMay stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades … Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis.
Polypeptides: Chondroitin sulfate proteoglycan 4Lysyl oxidase homolog 4
go.drugbank.com/bio_entities/BE0018464TargetHumansCatalyzes the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin, resulting in the formation of covalent cross-linkages, and the stabilization of collagen and elastin fibers
Polypeptides: Lysyl oxidase homolog 4Synonyms: Lysyl oxidase-like protein 4Lamivudine
go.drugbank.com/drugs/DB00709ApprovedInvestigationalA reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. … It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Synonyms: beta-L-2',3'-Dideoxy-3'-thiacytidine, beta-L-3'-Thia-2',3'-dideoxycytidineMixtures: N/A, N/ADarifenacin
go.drugbank.com/drugs/DB00496ApprovedInvestigationalDarifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. … It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.
Synonyms: (S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-α,α-diphenyl-3-pyrrolidineacetamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsTriclosan
go.drugbank.com/drugs/DB08604ApprovedAn aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. … It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards
Synonyms: 5-Chloro-2-(2,4-dichloro-phenoxy)-phenol, 2,4,4'-Trichloro-2'-hydroxydiphenyl etherMixtures: PREVENT 2 EN 1, T-Chem E2 Rated