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Acetaminophen
go.drugbank.com/drugs/DB00316ApprovedInvestigationalrisk of neurological conditions such as autism and ADHD in children. … Acetaminophen (paracetamol), also commonly known as _Tylenol_, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization
Synonyms: p-acetamidophenol, p-acetaminophenolInternational brands: Oraphen-PDDutasteride
go.drugbank.com/drugs/DB01126ApprovedInvestigationalIt is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. … Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Ag-dutasterideCoal tar
go.drugbank.com/drugs/DB11082ApprovedCoal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas.
Mixtures: P&s Plus, Polytar AF ShampooProducts: Pc-tarLosartan
go.drugbank.com/drugs/DB00678ApprovedInvestigational[L7423] Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and hydrochlorothiazide. … [L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough.
Mixtures: LORZAAR PL FORTE100/12.5MG, Ag-losartan HctzCategories: P-glycoprotein inhibitors, P-glycoprotein substratesDiazepam
go.drugbank.com/drugs/DB00829ApprovedIllicitInvestigationalVet approvedIt is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal … A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: AA-Diazepam Tablet 5mg, AA-Diazepam Tablet 10mgDoxorubicin
go.drugbank.com/drugs/DB00997ApprovedInvestigationalDoxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970. … [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexProducts: DOXORUBICIN AU 2MG/ML 10MG, DOXORUBICIN AU 2MG/ML 50MGEscitalopram
go.drugbank.com/drugs/DB01175ApprovedInvestigationalan inactive enantiomer. … Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram].
Categories: Monoamine Oxidase A Substrates, P-glycoprotein substratesProducts: Ag-escitalopram, Ag-escitalopram TabletsMonopotassium phosphate
go.drugbank.com/drugs/DB09413ApprovedInvestigationalVet approvedIt is a source of phosphorus and potassium as well as a buffering agent. It can be used in fertilizer mixtures to reduce escape of ammonia by keeping pH low. … Monopotassium phosphate, MKP, (also potassium dihydrogenphosphate, KDP, or monobasic potassium phosphate), KH2PO4, is a soluble salt of potassium and the dihydrogen phosphate ion.
Mixtures: Av-Phos 250 Neutral, BİOFLEKS İZOLEKS-S pH 7,4 IV İNFÜZYONLUK ÇÖZELTİ, 500 ML (PVC TORBA) SETLİCategories: Compounds used in a research, industrial, or household settingCholecalciferol
go.drugbank.com/drugs/DB00169ApprovedInvestigationalNutraceuticalStructurally, ergocalciferol differs from cholecalciferol in that it possesses a double bond between C22 and C23 and has an additional methyl group at C24 [L5689]. … Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation
Mixtures: Advanced AM PM, Advanced AM PMCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsPropranolol
go.drugbank.com/drugs/DB00571ApprovedInvestigationalPropranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. … [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904]
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, P-glycoprotein inhibitorsProducts: PROPRANOLOL AL 40, PROPRANOLOL AL 80