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Displaying results 431 - 440 of 6198 in total

Drug
Oxybenzone
go.drugbank.com/drugs/DB01428
Approved
It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays. … Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents.
Mixtures: You Rebel, Benefit You Rebel SPF 15
Drug
Benzoyl peroxide
go.drugbank.com/drugs/DB09096
ApprovedInvestigational
Benzoyl peroxide is a commonly used drug in topical treatments for acne. It has been formulated as products with either a single active ingredient, or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond ...
Mixtures: Target Up and Up 3 Step Acne System, Target Up and Up 3 Step Acne SystemProducts: Target Up and Up Acne Medication, Target Up and Up Acne Spot Treatment
Drug
Nimesulide
go.drugbank.com/drugs/DB04743
ApprovedWithdrawn
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and...
Products: UL-FLAM
Drug
Filgrastim
go.drugbank.com/drugs/DB00099
ApprovedInvestigational
It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_. … [L40714] Filgrastim was approved in the US in 1991 and there are biosimilars available with similar therapeutic indications.[A245858] Tbo-filgrastim was approved by the FDA on August 29, 2012.
Products: NEUPOGEN 30 MIO U 0.3MG/ML VIAL, INMUNEF 30 UI SOLUCION INYECTABLE
Drug
ssCART-19 cells
go.drugbank.com/drugs/DB18653
Investigational
ssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6).
Synonyms: autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6) (also termed ssCART-19 cells)
Target
Multifunctional protein CAD
go.drugbank.com/bio_entities/BE0002227
TargetEnzymeHumans
Multifunctional protein that encodes the first 3 enzymatic activities of the de novo pyrimidine pathway: carbamoylphosphate synthetase (CPSase; EC 6.3.5.5), aspartate transcarbamylase (ATCase; EC 2.1.3.2) and dihydroorotase (DHOase; EC 3...
Polypeptides: Multifunctional protein CAD
Drug
Urea
go.drugbank.com/drugs/DB03904
ApprovedInvestigational
A compound formed in the liver from ammonia produced by the deamination of amino acids.
Mixtures: Ti-U-lac Lotion, Ti-U-lac HC LotionProducts: UO CREAM, U O CREAM 10%
Drug
Bemotrizinol
go.drugbank.com/drugs/DB11206
Approved
Bemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays. … It is claimed to be photostable, which increases its onset of action and its efficiency in providing protection against UV-rays upon topical application [A19212, A32909].
Mixtures: Uv+age Daily, Ultra-light Uv Lotion
Drug
Linezolid
go.drugbank.com/drugs/DB00601
ApprovedInvestigational
Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. … [A233425] A second member of this class, [tedizolid], was approved by the FDA in 2014 and is considered generally more effective and tolerable than its predecessor.
Products: DILOZELD-UF 2MG/ML SOLUCIÓN PARA INFUSIÓN
Drug
Drometrizole trisiloxane
go.drugbank.com/drugs/DB11585
Approved
The compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia
Mixtures: Rosaliac Uv, Uv+age Daily