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Amodiaquine
go.drugbank.com/drugs/DB00613ApprovedInvestigationalA 4-aminoquinoquinoline compound with anti-inflammatory properties.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesImatinib
go.drugbank.com/drugs/DB00619ApprovedInvestigational[A249305] It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. … Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001.
Synonyms: α-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidideCategories: P-glycoprotein inhibitors, P-glycoprotein substratesTriamcinolone
go.drugbank.com/drugs/DB00620ApprovedInvestigationalVet approved[L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses. … Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis.
Synonyms: 9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dioneInternational brands: Omcilon-ANicardipine
go.drugbank.com/drugs/DB00622ApprovedInvestigationalA potent calcium channel blockader with marked vasodilator action. … It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Cardene SR, CARDIBLOC-SR CAPSULE 40 mgTestosterone
go.drugbank.com/drugs/DB00624ApprovedInvestigationalTestosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.
Synonyms: 4-androsten-17β-ol-3-one, 17beta-hydroxy-4-androsten-3-oneInternational brands: Bio-T-Gel, Synandrol FClorazepic acid
go.drugbank.com/drugs/DB00628ApprovedIllicitClorazepic acid (clorazepate) is a water-soluble benzodiazepine with muscle-relaxant and anticonvulsant actions effective in the treatment of anxiety. … In September 2020, a black box warning describing these risks was included on the product label of benzodiazepines as per FDA regulation.
Synonyms: 7-chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acidInternational brands: Zetran-5Clofarabine
go.drugbank.com/drugs/DB00631ApprovedInvestigationalClofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. … Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed.
Synonyms: (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol, 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenineCategories: Heterocyclic Compounds, 2-Ring, OCT2 Substrates with a Narrow Therapeutic IndexPrednisone
go.drugbank.com/drugs/DB00635ApprovedInvestigationalVet approvedA synthetic anti-inflammatory glucocorticoid derived from [cortisone].[A187463] It is biologically inert and converted to [prednisolone] in the liver.
Synonyms: 1, 2-DehydrocortisoneCategories: CHOP-R chemotherapy regimen, P-glycoprotein inducersDyclonine
go.drugbank.com/drugs/DB00645ApprovedInvestigationalDyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It may also be found in some Cepacol sore throat spray products.
Synonyms: 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone, 4-n-butoxy-β-(1-piperidyl)propiophenoneProducts: Sucrets MS WintergreenDyphylline
go.drugbank.com/drugs/DB00651ApprovedWithdrawnDyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.
Synonyms: 7-(β,γ-dihydroxypropyl)theophylline, (1,2-dihydroxy-3-propyl)thiophyllinMixtures: Dy G, Dilex-G 400