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Tosedostat
go.drugbank.com/drugs/DB11781InvestigationalIt has demonstrated anti-tumour activity in a number of models of cancer, both as a single agent and in synergy with cytotoxic agents such as carboplatin and paclitaxel. … Tosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas Cancer, Multiple Myeloma, and Pancreatic Cancer, among others.
Diazepinomicin
go.drugbank.com/drugs/DB12420InvestigationalDiazepinomicin has been used in trials studying the treatment of Glioblastoma Multiforme. … Diazepinomicin is a natural product derived from a non-pathogenic micro-organism.
Categories: Heterocyclic Compounds, 3-RingSynonyms: 4,6,8-trihydroxy-10-(3,7,11-trimethyldodeca-2,6,10-trienyl)-5,10-dihydrodibenzo(b,e)(1,4)diazepin-11-oneAIT-034
go.drugbank.com/drugs/DB06106ExperimentalAIT-034 is a distinct chemical analog of hypoxanthine and pyrollidone that has been demonstrated in animal studies to enhance memory and to reverse memory deficits in severely impaired animals that do … There is some evidence that AIT-034 could complement Neotrofin as a treatment for Alzheimer's disease and dementia.
Insulin human
go.drugbank.com/drugs/DB00030ApprovedInvestigationalHuman Insulin is a 51 residue peptide hormone produced by recombinant DNA technology by inserting the human insulin gene into Escherichia coli bacteria or Saccharomyces cerevisiae. … Insulin is typically prescribed later in the course of T2D, after trying several oral medications such as [DB00331], [DB01120], or [DB01261] have been tried, when sufficient damage has been caused to pancreatic
Mixtures: HUMULIN ® 70/30, HUMULIN ® 70/30Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProstaglandin E synthase 3
go.drugbank.com/bio_entities/BE0002480TargetHumansMolecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory
Synonyms: Progesterone receptor complex p23SLAM family member 7
go.drugbank.com/bio_entities/BE0003492TargetHumansSelf-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family.
Synonyms: CD2-like receptor-activating cytotoxic cellsTyramine
go.drugbank.com/drugs/DB08841InvestigationalNutraceuticalTyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. … There have been reports of hypertensive crisis in patients ingesting tyramine-rich diet in conjunction with monoamine oxidase inhibitors (MAOIs).
Propacetamol
go.drugbank.com/drugs/DB09288Investigational[A7892] It is not available in the United States but this prodrug has been widely used in other countries such as France since 1985.[L1505] … [A32051] It is a derivative of [acetaminophen], or paracetamol, with the molecular formula glycine, N, N-diethyl-,4-(acetylamino)phenyl ester.
Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesVoltage-gated inwardly rectifying potassium channel KCNH7
go.drugbank.com/bio_entities/BE0000699TargetHumansPore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel (PubMed:32723862). Exhibits faster activation and deactivation kinetics and slow inactivation at membrane potentials positive to 240 mV, resulting in the...
Synonyms: Ether-a-go-go-related gene potassium channel 3Antigen peptide transporter 1
go.drugbank.com/bio_entities/BE0003109TransporterHumansABC transporter associated with antigen processing. In complex with TAP2 mediates unidirectional translocation of peptide antigens from cytosol to endoplasmic reticulum (ER) for loading onto MHC class I (MHCI) molecules (PubMed:25377891,...
Synonyms: Really interesting new gene 4 protein