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Displaying results 4411 - 4420 of 10000 in total
  1. Drug

    Tositumomab

    go.drugbank.com/drugs/DB00081
    ApprovedWithdrawn

    Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda chains of 220 residues). It is produced in an antibiotic-free culture of mammalian cells. … It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).

  2. Drug

    Acifluorfen

    go.drugbank.com/drugs/DB07338
    Experimental

    Acifluorfen is a protoporphyrinogen oxidase inhibitor.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Lasalocid

    go.drugbank.com/drugs/DB11423
    ExperimentalVet approved

    Lasalocid is an agent that presents antibacterial and coccidiostat activities. It is produced by strains of _Streptomyces lasaliensis_.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring
  4. Drug

    Tolu balsam

    go.drugbank.com/drugs/DB11223
    Investigational

    Synonyms: bálsamo de ToluCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Mersalyl

    go.drugbank.com/drugs/DB09338
    Experimental

    Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. It is an outdated drug, and its approval has been discontinued by the FDA. … Interestingly, it has been found to have antiviral properties in mice [L1584].

  6. Drug

    MLN576

    go.drugbank.com/drugs/DB06517
    Experimental

    XR11576 (MLN576) is a novel monophenazine with a mechanism of action that includes interaction with both topoisomerase (Topo) I and II.[A234609]

    Categories: Topoisomerase I Inhibitors, Topoisomerase II Inhibitors
  7. Drug

    Dehydroascorbic acid

    go.drugbank.com/drugs/DB08830
    Experimental

    Dehydroascorbic acid as well as ascorbic acid are both termed Vitamin C, but the latter is the main form found in humans. … In the body, both dehydroascorbic acid and ascorbic acid have similar biological activity as antivirals but dehydroascorbic acid also has neuroprotective effects.

    Categories: Vitamin C and analoguesSynonyms: L-threo-2,3-hexodiulosonic acid, γ-lactone, L-dehydroascorbate
  8. Drug

    Metrifonate

    go.drugbank.com/drugs/DB11473
    ExperimentalVet approved

    Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester
  9. Drug

    Z-Val-Ala-Asp fluoromethyl ketone

    go.drugbank.com/drugs/DB07744
    Experimental

    It does not require an esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(O-Me) fluoromethyl ketone. … Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: N-[(Benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxo-2-butanyl]-L-alaninamide, Z-VAD-FMK
  10. Drug

    Girentuximab

    go.drugbank.com/drugs/DB05304
    Investigational

    Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).