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Displaying results 4411 - 4420 of 10000 in total
  1. Target

    Chain A, Red Copper Protein Nitrosocyanin

    go.drugbank.com/bio_entities/BE0002711
    TargetNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)

    Polypeptides: Chain A, Red Copper Protein Nitrosocyanin
  2. Target

    Peptidyl-prolyl cis-trans isomerase A

    go.drugbank.com/bio_entities/BE0004194
    TargetEscherichia coli (strain K12)

    PPIases accelerate the folding of proteins (Probable). It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (PubMed:2190212).

    Polypeptides: Peptidyl-prolyl cis-trans isomerase ASynonyms: PPIase A, Rotamase A
  3. Target

    Platelet-derived growth factor subunit A

    go.drugbank.com/bio_entities/BE0010246
    TargetHumans

    Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum ...

    Polypeptides: Platelet-derived growth factor subunit ASynonyms: PDGF subunit A, Platelet-derived growth factor A chain
  4. Drug

    Rivastigmine

    go.drugbank.com/drugs/DB00989
    ApprovedInvestigational

    Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. … Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type.

    Synonyms: m-((S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate, (S)-3-(1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamateCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Icatibant

    go.drugbank.com/drugs/DB06196
    ApprovedInvestigational

    [A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema. … [L49776,L49781] The FDA approval was based on positive results obtained from 3 double-blind, randomized, controlled clinical trials known as FAST 1, 2, and 3, where a median time to almost complete symptom

    Categories: Drugs Used in Hereditary AngioedemaProducts: Icatibant Reddy 30 mg/3 ml Injektionslösung in einer Fertigspritze, İKTU 30 MG/3 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET
  6. Drug

    Lacosamide

    go.drugbank.com/drugs/DB06218
    ApprovedInvestigational

    Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. … Lacosamide exhibits a stereoselective mode of interaction with sodium channels.

    Mixtures: ELEPSİ 50 MG+100 MG TEDAVİYE BAŞLAMA PAKETİ, 42 ADET, ELEPSİ 50 MG+100 MG TEDAVİYE BAŞLAMA PAKETİ, 42 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Drug

    Phenytoin

    go.drugbank.com/drugs/DB00252
    ApprovedInvestigationalVet approved

    Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants. … [A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications

    Mixtures: Dilantin W Phenobarbital 15mg, Dilantin W Phenobarbital 30mg CapCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index
  8. Drug

    Bilastine

    go.drugbank.com/drugs/DB11591
    Approved

    Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingProducts: BILASTINA EG, ELHIST ® 20 MG
  9. Drug

    Phenylephrine

    go.drugbank.com/drugs/DB00388
    ApprovedInvestigational

    Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and induce local vasoconstriction. … [A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s.[A187376] Phenylephrine was granted FDA approval in 1939.[L9413]

    Synonyms: (−)-m-hydroxy-α-(methylaminomethyl)benzyl alcohol, l-(3-Hydroxyphenyl)-N-methylethanolamineInternational brands: AK-Dilate, AK-Nefrin
  10. Drug

    Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate

    go.drugbank.com/drugs/DB14106
    ApprovedInvestigational

    Tetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.[L12744]

    Synonyms: Tetrakis (2-methoxyisobutyl isonitrile) copper (I) tetrafluoroborate, Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborateProducts: MIBITEC 1 mg Kit für ein radioaktives Arzneimittel, CardioTOP 1 mg Kit für ein radioaktives Arzneimittel