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Displaying results 4421 - 4430 of 10000 in total
  1. Drug

    Nigericin

    go.drugbank.com/drugs/DB14056
    Experimental

    A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)

    Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingSynonyms: Helixin C, Azalomycin M
  2. Drug

    Valinomycin

    go.drugbank.com/drugs/DB14057
    Experimental

    It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. … (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: Potassium ionophore I
  3. Drug

    Basifungin

    go.drugbank.com/drugs/DB14058
    Experimental

    Basifungin, also known as _aureuobacidin A_, is a phosphorylceramide synthase inhibitor [L2960], [A33381].

    Synonyms: Aureobasidin A
  4. Drug

    Hycanthone

    go.drugbank.com/drugs/DB14061
    Experimental

    Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.

    Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 3-RingSynonyms: 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one, 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one
  5. Drug

    Concanamycin A

    go.drugbank.com/drugs/DB14062
    Experimental

    Concanamycin A is an H+-ATPase (vacuolar) inhibitor.

    Categories: P-glycoprotein inhibitorsSynonyms: Concanamycin A
  6. Drug

    Tetrandrine

    go.drugbank.com/drugs/DB14066
    Investigational

    Synonyms: (S,S)-Tetrandrine, D-TetrandrineCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  7. Drug

    Dofequidar

    go.drugbank.com/drugs/DB14067
    Investigational

    Dofequidar is an antineoplastic agent.

    Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-Ring
  8. Drug

    HM-30181

    go.drugbank.com/drugs/DB14070
    Investigational

    Categories: ATP Binding Cassette Transporter, Subfamily B, Member 1, antagonists & inhibitors, P-glycoprotein inhibitors
  9. Drug

    Desmethylsertraline

    go.drugbank.com/drugs/DB14071
    Experimental

    Desmethylsertraline is a metabolite of sertraline.

    Categories: P-glycoprotein inhibitorsSynonyms: N-Demethylsertraline, N-Desmethylsertraline
  10. Drug

    Reversin 121

    go.drugbank.com/drugs/DB14072
    Experimental

    Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance.

    Categories: P-glycoprotein inhibitors