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Displaying results 4421 - 4430 of 10000 in total
  1. Drug

    Magrolimab

    go.drugbank.com/drugs/DB16225
    Investigational

    Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).

    Synonyms: )) (8.8.10) (1-117)-homo sapiens ighg4*01 (ch1 (118-2, Immunoglobulin g4-kappa, anti-(homo sapiens cd47 (integrin associated protein, iap, mer6, oa3)), monoclonal antibodygamma4 heavy chain (1-444) (vh (homo sapiens ighv1-3*01 (87.8%)-(ighd)-ighj4*01 (100%
  2. Drug

    Meclizine

    go.drugbank.com/drugs/DB00737
    ApprovedInvestigational

    Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties.

    Mixtures: VELOXIN TABLET 25/50mgCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  3. Drug

    Hydroquinone

    go.drugbank.com/drugs/DB09526
    ApprovedInvestigational

    As a result of these concerns, hydroquinone has been banned in the EU and UK. … Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention

    Mixtures: Porcelana 24 Hour Skin Lightening, I-max Lightening 5Categories: Compounds used in a research, industrial, or household setting
  4. Target

    2-iminobutanoate/2-iminopropanoate deaminase

    go.drugbank.com/bio_entities/BE0002076
    TargetEscherichia coli (strain K12)

    It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia.

    Polypeptides: 2-iminobutanoate/2-iminopropanoate deaminaseFunction: 2-iminobutanoate deaminase activity
  5. Target

    2-hydroxychromene-2-carboxylate isomerase

    go.drugbank.com/bio_entities/BE0003759
    TargetPseudomonas putida

    Catalyzes the reversible glutathione-dependent isomerization of 2-hydroxychromene-2-carboxylate (HCCA) to trans-O-hydroxybenzylidenepyruvate (THBPA).

    Polypeptides: 2-hydroxychromene-2-carboxylate isomeraseFunction: 2-hydroxychromene-2-carboxylate isomerase activity
  6. Target

    2'-hydroxybiphenyl-2-sulfinate desulfinase

    go.drugbank.com/bio_entities/BE0003956
    TargetRhodococcus sp. (strain IGTS8)

    Oxidizes 2-(2'-hydroxyphenyl)benzene sulphinate (HBPS) to 2-hydroxybiphenyl (HBP) plus sulfite (PubMed:31545606, PubMed:7574582, PubMed:7961424, PubMed:9308179, PubMed:9634856).

    Polypeptides: 2'-hydroxybiphenyl-2-sulfinate desulfinaseSynonyms: 2-(2-hydroxyphenyl)benzenesulfinate desulfinase
  7. Drug

    Human C1-esterase inhibitor

    go.drugbank.com/drugs/DB06404
    ApprovedInvestigational

    [L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a human genetic disorder caused by a shortage of C1 inhibitor activity that results in an overreaction … C1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor (hC1INH) isolated from human plasma.

    Products: CİNRYZE 500 IU/5 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 2 ADET
  8. Drug

    Azithromycin

    go.drugbank.com/drugs/DB00207
    ApprovedInvestigational

    Azithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl … Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175].

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: AZİTROTEK 500 MG FİLM TABLET, 2 TABLET, ZITROMAX SD 2 G/60 ML ORAL SÜSPANSIYON IÇIN UZATILMIŞ SALIMLI GRANÜL
  9. Drug

    Cefpodoxime

    go.drugbank.com/drugs/DB01416
    ApprovedInvestigationalVet approved

    Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.

    Mixtures: TEXEF PLUS 40 MG/62.5 MG GRANÜL İÇEREN SAŞE, 20 ADET, TEXEF PLUS 50 MG/62.5 MG GRANÜL İÇEREN SAŞE, 20 ADETCategories: Heterocyclic Compounds, 2-Ring
  10. Drug

    Racepinephrine

    go.drugbank.com/drugs/DB11124
    Approved

    Racepinephrine is a racemic mixture consisting of d-[DB00668] and l-[DB00668] enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist. … It is a bronchodilator used in the temporary relief of mild symptoms of intermittent asthma including wheezing, tightness of chest and shortness of breath.

    Mixtures: Gingicord W/epineph and Alum Size 2, Gingibraid W Epineph and Alum 2eCategories: Adrenergic alpha-2 Receptor Agonists, Adrenergic beta-2 Receptor Agonists