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Displaying results 4421 - 4430 of 10000 in total
  1. Target

    2'-hydroxybiphenyl-2-sulfinate desulfinase

    go.drugbank.com/bio_entities/BE0003956
    TargetRhodococcus sp. (strain IGTS8)

    Oxidizes 2-(2'-hydroxyphenyl)benzene sulphinate (HBPS) to 2-hydroxybiphenyl (HBP) plus sulfite (PubMed:31545606, PubMed:7574582, PubMed:7961424, PubMed:9308179, PubMed:9634856).

    Polypeptides: 2'-hydroxybiphenyl-2-sulfinate desulfinaseSynonyms: 2-(2-hydroxyphenyl)benzenesulfinate desulfinase
  2. Drug

    Human C1-esterase inhibitor

    go.drugbank.com/drugs/DB06404
    ApprovedInvestigational

    [L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a human genetic disorder caused by a shortage of C1 inhibitor activity that results in an overreaction … C1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor (hC1INH) isolated from human plasma.

    Products: CİNRYZE 500 IU/5 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 2 ADET
  3. Drug

    Etanercept

    go.drugbank.com/drugs/DB00005
    ApprovedInvestigational

    Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids. … It is used to treat or manage a variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and juvenile idiopathic poly-articular arthritis (JIA).

    Products: ENBREL MYCLIC PEN 50 MG ENJ. COZ.ICIN KULLANIMA HAZIR KALEM, 2 ADET, ETANAR ® 25 MG POLVO LIOFILIZADO
  4. Drug

    Azithromycin

    go.drugbank.com/drugs/DB00207
    ApprovedInvestigational

    Azithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl … Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175].

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: AZİTROTEK 500 MG FİLM TABLET, 2 TABLET, ZITROMAX SD 2 G/60 ML ORAL SÜSPANSIYON IÇIN UZATILMIŞ SALIMLI GRANÜL
  5. Drug

    Racepinephrine

    go.drugbank.com/drugs/DB11124
    Approved

    Racepinephrine is a racemic mixture consisting of d-[DB00668] and l-[DB00668] enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist. … It is a bronchodilator used in the temporary relief of mild symptoms of intermittent asthma including wheezing, tightness of chest and shortness of breath.

    Mixtures: Gingicord W/epineph and Alum Size 2, Gingibraid W Epineph and Alum 2eCategories: Adrenergic alpha-2 Receptor Agonists, Adrenergic beta-2 Receptor Agonists
  6. Target

    Transcobalamin-2

    go.drugbank.com/bio_entities/BE0000362
    CarrierTransporterHumans

    Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells

    Polypeptides: Transcobalamin-2Synonyms: TC-2
  7. Target

    Mucin-2

    go.drugbank.com/bio_entities/BE0001034
    TargetHumans

    Binds both Cu(2+) and its reduced form, Cu(1+), at two juxtaposed binding sites: Cu(2+), once reduced to Cu(1+) by vitamin C (ascorbate) or other dietary antioxidants, transits to the other binding site … 'Thick' mucus transits along the descending colon and is lubricated by a (2) 'thin' MUC2 mucus produced in the distal colon which adheres to the 'thick' mucus (By similarity)

    Polypeptides: Mucin-2Synonyms: MUC-2, Intestinal mucin-2
  8. Target

    Neopullulanase 2

    go.drugbank.com/bio_entities/BE0001427
    TargetThermoactinomyces vulgaris

    Hydrolyzes pullulan efficiently but only a small amount of starch. Endohydrolysis of 1,4-alpha-glucosidic linkages in pullulan to form panose. Cleaves also (1-6)-alpha-glucosidic linkages to form maltotriose.

    Polypeptides: Neopullulanase 2
  9. Target

    Syndecan-2

    go.drugbank.com/bio_entities/BE0002116
    TargetHumans

    Cell surface proteoglycan which regulates dendritic arbor morphogenesis

    Polypeptides: Syndecan-2
  10. Target

    Cytohesin-2

    go.drugbank.com/bio_entities/BE0002654
    TargetHumans

    Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Activates ARF factors through replacement of GDP with GTP (By similarity). The cell membrane form, in association with ARL4 ...

    Polypeptides: Cytohesin-2Synonyms: PH, SEC7 and coiled-coil domain-containing protein 2