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Displaying results 4421 - 4430 of 10000 in total
  1. Pathway

    Acylcarnitine 7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3-oxocyclopentyl]heptanoylcarnitine

    smpdb.ca/view/SMP0123552
    Metabolic

    inner membrane to once again form 7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3-oxocyclopentyl]heptanoyl-CoA and L-carnitine. 7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]- … 7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3-oxocyclopentyl]heptanoylcarnitine is an acylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5, Acetyl-CoA carboxylase 1
  2. Drug

    BR-007

    go.drugbank.com/drugs/DB18408
    Experimental

    Synonyms: (1-hydroxy-4-(((2-((4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethoxy)carbonyl)amino)butane-1,1-diyl)bis(hydrogen phosphonate)
  3. Drug

    Esatenolol

    go.drugbank.com/drugs/DB13443
    Experimental

    Esatenolol is a beta blocker.

    Synonyms: (S)-4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide, 2-(p-((2S)-2-hydroxy-3-(isopropylamino)propoxy)phenyl)acetamideCategories: s-atenolol, Cytochrome P-450 Substrates
  4. Drug

    N-[2-Hydroxy-2-(8-Isopropyl-6,9-Dioxo-2-Oxa-7,10-Diaza-Bicyclo[11.2.2]Heptadeca-1(16),13(17),14-Trien-11-Yl)-Ethyl]-N-(3-Methyl-Butyl)-Benzenesulfonamide,Inhibitor 3

    go.drugbank.com/drugs/DB03768
    Experimental

    Synonyms: N-[2-Hydroxy-2-(8-Isopropyl-6,9-Dioxo-2-Oxa-7,10-Diaza-Bicyclo[11.2.2]Heptadeca-1(16),13(17),14-Trien-11-Yl)-Ethyl]-N-(3-Methyl-Butyl)-Benzenesulfonamide,Inhibitor 3
  5. Drug

    Meloxicam

    go.drugbank.com/drugs/DB00814
    ApprovedInvestigationalVet approved

    [A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and intravenous formulations. … It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201]

    Mixtures: OCAM PROTECT ® 15 MG TABLETAS DE LIBERACION RETARDADA, OCAM PROTECT 15 MGCategories: Heterocyclic Compounds, 1-Ring, COX-2 Inhibitors
  6. Drug

    Isotretinoin

    go.drugbank.com/drugs/DB00982
    ApprovedInvestigational

    Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne. … [L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574]

    Mixtures: ISOTREXIN JEL, 30 G, ETREXİN % 2 + % 0.05 JELCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Drug

    Dexchlorpheniramine maleate

    go.drugbank.com/drugs/DB09555
    Approved

    Dexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine. … Dexchlorpheniramine has more pharmacological activity than the R and so is more potent than the racemic mixture.

    Mixtures: HUFADEXTA-M, INTUNAL-FCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Substrates
  8. Drug

    Ocrelizumab

    go.drugbank.com/drugs/DB11988
    ApprovedInvestigational

    [A18875,A251745] MS is a chronic, inflammatory, autoimmune disease of the central nervous system that leads to neurological disabilities and a significantly reduced quality of life. … [L42895] It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets B-cells that express the CD20 antigen.

    Products: OCREVUS 300 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, OCREVUS 300 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 2 ADET
  9. Drug

    Zinc

    go.drugbank.com/drugs/DB01593
    ApprovedInvestigational

    It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. … zinc as a marker of these diseases [L2097].

    Synonyms: ZnMixtures: Calcium With Mg Zn Mn Cu CR Si and Vit. C & D, FENYSOL-Z 40 MG + 15 MG/5 ML ŞURUP, 100 ML
  10. Drug

    Esketamine

    go.drugbank.com/drugs/DB11823
    ApprovedInvestigational

    [L5596,A175462] On March 5, 2019, the nasal spray drug, _esketamine_, also known as _Spravato_ (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression. … The intranasal route of administration for this drug allows for easy administration and a fast onset of action, which sets it apart from many other antidepressant agents that may take several weeks to

    Categories: Non-Competitive N-Methyl D-Aspartate (NMDA) Receptor Antagonists, Cytochrome P-450 SubstratesSynonyms: L-ketamine, (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone