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Displaying results 4431 - 4440 of 10000 in total
  1. Target

    Galectin-2

    go.drugbank.com/bio_entities/BE0003247
    TargetHumans

    This protein binds beta-galactoside. Its physiological function is not yet known

    Polypeptides: Galectin-2Synonyms: Gal-2, S-Lac lectin 2
  2. Target

    Acylphosphatase-2

    go.drugbank.com/bio_entities/BE0004569
    TargetHumans

    catalyzes the hydrolysis of acylphosphates compounds containing a carboxylphosphate bond

    Polypeptides: Acylphosphatase-2Synonyms: Acylphosphate phosphohydrolase 2
  3. Target

    Prohibitin-2

    go.drugbank.com/bio_entities/BE0009007
    TargetHumans

    Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcrip...

    Polypeptides: Prohibitin-2
  4. Target

    Angiopoietin-2

    go.drugbank.com/bio_entities/BE0010028
    TargetHumans

    Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling (PubMed:15284220, PubMed:19116766, PubMed:19223473, PubMed:9204896). Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1 (PubM...

    Polypeptides: Angiopoietin-2Synonyms: ANG-2
  5. Target

    Neuropilin-2

    go.drugbank.com/bio_entities/BE0010030
    TargetHumans

    High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF

    Polypeptides: Neuropilin-2Synonyms: Vascular endothelial cell growth factor 165 receptor 2
  6. Target

    Presenilin-2

    go.drugbank.com/bio_entities/BE0011014
    TargetHumans

    Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10497236, PubMed:1...

    Polypeptides: Presenilin-2Synonyms: PS-2, STM-2
  7. Target

    Kallikrein-2

    go.drugbank.com/bio_entities/BE0012874
    TargetHumans

    Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin

    Polypeptides: Kallikrein-2Synonyms: Tissue kallikrein-2
  8. Target

    Frizzled-2

    go.drugbank.com/bio_entities/BE0014542
    TargetHumans

    Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and...

    Polypeptides: Frizzled-2Synonyms: Fz-2
  9. Drug

    Progesterone

    go.drugbank.com/drugs/DB00396
    ApprovedInvestigationalVet approved

    Pharmaceutical progesterone is made from a plant source as a starting material and is chemically identical to progesterone of human ovarian origin [FDA label]. … A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609].

    Mixtures: SYNERGAL® DOBLE, Minoxidil 7% / Progesterone 0.1%Categories: P-glycoprotein inducers, P-glycoprotein inhibitors
  10. Drug

    Homatropine

    go.drugbank.com/drugs/DB11181
    Approved

    Homatropine hydrobromide has been administered as ophthalmic solutions as a cycloplegic to temporarily paralyze accomodation, and to induce mydriasis (the dilation of the pupil); however such therapeutic

    Products: HOMATRO 2%, Isopto Homatropine 2%