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Loteprednol etabonate
go.drugbank.com/drugs/DB14596ApprovedAs a nasal spray, it can be used for the treatment and management of seasonal allergic rhinitis. … It is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes
Dermatophagoides farinae
go.drugbank.com/drugs/DB10400ApprovedInvestigationalThis combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Dermatophagoides pteronyssinus
go.drugbank.com/drugs/DB10401ApprovedInvestigationalThis combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Arbaclofen Placarbil
go.drugbank.com/drugs/DB08892InvestigationalArbaclofen Placerbil is a prodrug of Arbaclofen, which is a selective gamma-amino-butyric acid type B receptor agonist and the R-enantiomer of baclofen. … It was discovered, and has been patented by XenoPort as a new chemical entity with an improved pharmacokinetic profile compared to baclofen, which allows for sustained release properties.
Categories: GABA-B Receptor AgonistsParecoxib
go.drugbank.com/drugs/DB08439ApprovedInvestigationalAs it is injectable, it can be used perioperatively when patients are unable to take oral medications. … Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union.
Oveporexton
go.drugbank.com/drugs/DB21680ApprovedOveporexton is an orally administered orexin receptor 2 (OX2R) agonist used to treat narcolepsy type 1 (NT1). … [L64068,L64069] It is the first orexin receptor agonist approved by the FDA and the first medicine to treat NT1 by targeting its underlying cause rather than individual symptoms.
Categories: Orexin receptor agonistsCalcium threonate
go.drugbank.com/drugs/DB11168ApprovedWithdrawnL-threonate is an active metabolite of vitamin C that mediates a stimulatory action on vitamin C uptake [A27266]. … It is found in dietary supplements as a source of L-threonate used in the treatment of calcium deficiency and prevention of osteoporosis.
ND1251
go.drugbank.com/drugs/DB05132ExperimentalND1251 is an orally active phosphodiesterase-4 (PDE4) inhibitor, a mechanism clinically proven to play a role in alleviating symptoms of depression. … ND1251 is a very potent compound with a large safety margin.
Ammonium molybdate
go.drugbank.com/drugs/DB11128InvestigationalMolybdenum is an essential element that is present in enzymes including xanthine oxidase, sulfite oxidase, and aldehyde oxidase. … Ammonium molybdate is a source of molybdenum that exists in several hydrate forms. It is intravenously administered as an additive to solutions for Total Parenteral Nutrition (TPN).
Categories: Compounds used in a research, industrial, or household settingImidafenacin
go.drugbank.com/drugs/DB09262InvestigationalImidafenacin is an antispasmodic agent with anticholinergic effects. It antagonizes muscarinic receptors in the bladder to reduce the frequency of urination in the treatment of overactive bladder. … It is marketed in Japan under the tradenames Staybla by Ono Pharmaceutical and Uritos by Kyojin Pharmaceutical.