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Displaying results 4451 - 4460 of 10000 in total
  1. Target

    Hexokinase-2

    go.drugbank.com/bio_entities/BE0009792
    TargetHumans

    Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed:23185017, PubMed:26985301, PubMed:29298880). Mediates the initial s...

    Polypeptides: Hexokinase-2
  2. Target

    Semenogelin-2

    go.drugbank.com/bio_entities/BE0009916
    TargetHumans

    Participates in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions and ejaculated spermatozoa

    Polypeptides: Semenogelin-2
  3. Target

    Cadherin-2

    go.drugbank.com/bio_entities/BE0012803
    TargetHumans

    Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regula...

    Polypeptides: Cadherin-2
  4. Target

    Dynamin-2

    go.drugbank.com/bio_entities/BE0013402
    TargetHumans

    Catalyzes the hydrolysis of GTP and utilizes this energy to mediate vesicle scission at plasma membrane during endocytosis and filament remodeling at many actin structures during organization of the actin cytoskeleton (PubMed:15731758, P...

    Polypeptides: Dynamin-2Synonyms: Dynamin 2
  5. Target

    Perilipin-2

    go.drugbank.com/bio_entities/BE0018750
    TargetHumans

    Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets

    Polypeptides: Perilipin-2
  6. Target

    Interleukin-2

    go.drugbank.com/bio_entities/BE0001029
    TargetHumans

    Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance (PubMed:6438535). Binds to a rec...

    Polypeptides: Interleukin-2Synonyms: IL-2
  7. Target

    Carboxylesterase 2

    go.drugbank.com/bio_entities/BE0003048
    TargetPseudomonas fluorescens

    Hydrolyzes carboxylic ester bonds with relatively broad substrate specificity.

    Polypeptides: Carboxylesterase 2
  8. Target

    Sialidase-2

    go.drugbank.com/bio_entities/BE0003200
    TargetHumans

    Cleaves milk oligosaccharide alpha-(2->3)-sialyllactose, but is inactive toward alpha-(2->6)-sialyllactose isomer. … Displays preference for alpha-(2->3)-sialylated GD1a and GT1B gangliosides over alpha-(2->8)-sialylated GD1b, in both monomeric forms and micelles.

    Polypeptides: Sialidase-2Synonyms: Neuraminidase-2, N-acetyl-alpha-neuraminidase 2
  9. Target

    Trypsin-2

    go.drugbank.com/bio_entities/BE0004529
    TargetHumans

    In the ileum, may be involved in defensin processing, including DEFA5

    Polypeptides: Trypsin-2Synonyms: Serine protease 2
  10. Target

    Metallothionein-2

    go.drugbank.com/bio_entities/BE0004779
    EnzymeTargetHumans

    Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids

    Polypeptides: Metallothionein-2Synonyms: MT-2