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Valbenazine
go.drugbank.com/drugs/DB11915ApprovedInvestigationalThe reduction in chorea severity was observed as early as 2 weeks after starting treatment with an initial dose of 40 mg.[L47910] … [A261165] However, challenges in using [tetrabenazine] as a treatment of tardive dyskinesia included frequent dosing and safety and tolerability concerns.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: REMLEAS HARD CAPSULES 40 MG, REMLEAS™ hard capsules 40mgAcylcarnitine (7E)-5-Hydroxydodec-7-enoylcarnitine
smpdb.ca/view/SMP0124015Metabolic(7E)-5-Hydroxydodec-7-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (7E)-5-hydroxydodec-7-enoyl-CoA reacts with L-carnitine to form (7E)-5-hydroxydodec-7-enoylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine (3Z)-5-Hydroxytetradec-3-enoylcarnitine
smpdb.ca/view/SMP0124155Metabolic(3Z)-5-Hydroxytetradec-3-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (3Z)-5-hydroxytetradec-3-enoyl-CoA reacts with L-carnitine to form (3Z)-5-hydroxytetradec-3-enoylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine (5Z)-3-Hydroxytetradec-5-enedioylcarnitine
smpdb.ca/view/SMP0124165Metabolic(5Z)-3-Hydroxytetradec-5-enedioylcarnitine is an acylcarnitine. … -5-enedioyl-CoA and L-carnitine. (5Z)-3-Hydroxytetradec-5-enedioyl-CoA then enters into the mitochondrial beta-oxidation pathway to form aceytl-CoA.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Phosphatidylcholine Biosynthesis PC(20:5(5Z,8Z,11Z,14Z,17Z)/20:5(5Z,8Z,11Z,14Z,17Z))
smpdb.ca/view/SMP0014785MetabolicPhosphatidylcholines (PC) are a class of phospholipids that incorporate a phosphocholine headgroup into a diacylglycerol backbone. They are the most abundant phospholipid in eukaryotic cell membranes and has both structural and signallin...
Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 morePhosphatidylcholine Biosynthesis PC(20:5(5Z,8Z,11Z,14Z,17Z)/22:5(7Z,10Z,13Z,16Z,19Z))
smpdb.ca/view/SMP0014791MetabolicPhosphatidylcholines (PC) are a class of phospholipids that incorporate a phosphocholine headgroup into a diacylglycerol backbone. They are the most abundant phospholipid in eukaryotic cell membranes and has both structural and signallin...
Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 morePhosphatidylcholine Biosynthesis PC(22:5(4Z,7Z,10Z,13Z,16Z)/22:5(4Z,7Z,10Z,13Z,16Z))
smpdb.ca/view/SMP0014935MetabolicPhosphatidylcholines (PC) are a class of phospholipids that incorporate a phosphocholine headgroup into a diacylglycerol backbone. They are the most abundant phospholipid in eukaryotic cell membranes and has both structural and signallin...
Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 morePhosphatidylcholine Biosynthesis PC(22:5(7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z))
smpdb.ca/view/SMP0014964MetabolicPhosphatidylcholines (PC) are a class of phospholipids that incorporate a phosphocholine headgroup into a diacylglycerol backbone. They are the most abundant phospholipid in eukaryotic cell membranes and has both structural and signallin...
Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 morePhosphatidylethanolamine Biosynthesis PE(20:5(5Z,8Z,11Z,14Z,17Z)/22:5(4Z,7Z,10Z,13Z,16Z))
smpdb.ca/view/SMP0015630MetabolicPhosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phospha...
Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 morePhosphatidylethanolamine Biosynthesis PE(20:5(5Z,8Z,11Z,14Z,17Z)/22:5(7Z,10Z,13Z,16Z,19Z))
smpdb.ca/view/SMP0015631MetabolicPhosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phospha...
Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more