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Pyrroloquinoline Quinone
go.drugbank.com/drugs/DB03205InvestigationalA pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES. [PubChem]
Sulodexide
go.drugbank.com/drugs/DB06271ApprovedInvestigationalWithdrawnSulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).
Nadifloxacin
go.drugbank.com/drugs/DB12447InvestigationalNadifloxacin has been used in trials studying the treatment of Acne Vulgaris.
Nitarsone
go.drugbank.com/drugs/DB11437ExperimentalVet approvedIt is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing blackhead disease. It is marketed as Histostat by Zoetis, a publicly traded subsidiary of Pfizer.
LM-609
go.drugbank.com/drugs/DB05787ExperimentalLM-609 (Vitaxin) is an artificial antibody that targets a protein on the surface of newly forming blood vessels, as well as on certain tumors. … In addition to cancer, the protein has been implicated in bone destruction in rheumatoid arthritis and the inflammatory process in psoriasis.
Pimethixene
go.drugbank.com/drugs/DB13292ApprovedIt is an anticholinergic used in the treatment of bronchitis.
XL281
go.drugbank.com/drugs/DB05190InvestigationalXL281 is a novel anticancer compound designed to potently inhibit the RAS/RAF/MEK/ERK signaling pathway. … Mutational activation of RAS occurs in about 30 percent of all human tumors, including non-small cell lung, pancreatic, and colon cancer.
Candoxatrilat
go.drugbank.com/drugs/DB11623ExperimentalA potent inhibitor of neutral endopeptidase (NEP, neprilysin, EC 3.4.24.11), it is used as its 2,3-dihydro-1H-inden-5-yl ester prodrug in the treatment of chronic heart failure.
Vicriviroc
go.drugbank.com/drugs/DB06652InvestigationalThis drug was developed by Schering-Plough. … Vicriviroc, also known as SCH 417690 and SCH-D, is currently in clinical trials for the management of HIV-1.
Basic Fibroblast Growth Factor
go.drugbank.com/drugs/DB14131InvestigationalIt has a 55 percent amino acid residue identity to Fibroblast Growth Factor 1 and has potent heparin-binding activity. … It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (Fibroblast Growth Factor 1).