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Displaying results 4521 - 4530 of 10000 in total
  1. Drug

    Talmapimod

    go.drugbank.com/drugs/DB05412
    Investigational

    Talmapimod is the first-generation oral p38 MAP kinase inhibitor developed by Scios. It has shown to be effective to cure inflammatory diseases such as Rheumatoid Arthritis.

  2. Target

    Prostaglandin E synthase 3

    go.drugbank.com/bio_entities/BE0002480
    TargetHumans

    Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory

    Synonyms: Progesterone receptor complex p23
  3. Target

    SLAM family member 7

    go.drugbank.com/bio_entities/BE0003492
    TargetHumans

    Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family.

    Synonyms: CD2-like receptor-activating cytotoxic cells
  4. Drug

    2-Methoxyestradiol

    go.drugbank.com/drugs/DB02342
    Investigational

    2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis). … It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis.

  5. Drug

    m-Chlorophenylpiperazine

    go.drugbank.com/drugs/DB12110
    Investigational

    m-Chlorophenylpiperazine has been used in trials studying the treatment of Alcoholism.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor Agonists
  6. Drug

    Parathyroid hormone

    go.drugbank.com/drugs/DB05829
    ApprovedInvestigational

    The name Preos and the New Drug Application is pending approval by the U.S. Food and Drug Administration (FDA). … Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence

  7. Drug

    Mebutamate

    go.drugbank.com/drugs/DB06797
    Approved

    Mebutamate is a sedative and anxiolytic drug with anti-hypertensive (blood pressure lowering) effects comparable to those of other barbiturates but is only around 1/3rd the potency of secobarbital as a

  8. Drug

    Enalkiren

    go.drugbank.com/drugs/DB03395
    Experimental

    Categories: Agents Acting on the Renin-Angiotensin System
  9. Drug

    Oxitriptan

    go.drugbank.com/drugs/DB02959
    ApprovedInvestigationalNutraceuticalWithdrawn

    More study is needed to determine efficacy in treating depression. … 5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in

  10. Drug

    Dirucotide

    go.drugbank.com/drugs/DB04921
    Investigational

    In particular, the sequence prepared is a 17 amino acid chain that is identical to a section of myelin basic protein (MBP) that is found in humans. … Dirucotide has been developed for the treatment of multiple sclerosis (MS). Developed at the University of Alberta, dirucotide is being investigated by BioMS Medical Corp.