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Displaying results 4521 - 4530 of 10000 in total
  1. Drug

    Tropicamide

    go.drugbank.com/drugs/DB00809
    Approved

    [A230103] Usually available in ophthalmic formulations, tropicamide is used to cause mydriasis and cycloplegia for eye exams or ocular procedures. … [L32178] Oral tropicamide has been investigated as a potential drug to relieve sialorrhea in patients with Parkinson's Disease.[A229958]

    Mixtures: T-P OFTENO, T-P OFTENOCategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Deutivacaftor

    go.drugbank.com/drugs/DB15141
    ApprovedInvestigational

    It is used alongside CFTR correctors to increase the quantity and function of CFTR at the cell surface in patients with cystic fibrosis. … [L52275,A179677] Deutivacaftor was first approved by the US FDA in December 2024 in combination with two CFTR correctors - [tezacaftor] and [vanzacaftor] - for the treatment of patients with responsive

    Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: D9-Ivacaftor
  3. Drug

    3,3'-diindolylmethane

    go.drugbank.com/drugs/DB11875
    Investigational

    Diindolylmethane has been used in trials studying the prevention and treatment of SLE, Prostate Cancer, Cervical Dysplasia, Stage I Prostate Cancer, and Stage II Prostate Cancer, among others.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-Ring
  4. Drug

    Methimazole

    go.drugbank.com/drugs/DB00763
    ApprovedInvestigational

    in pregnancy due to a perceived lower risk of teratogenic effects. … [A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949[A184502] and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive

    Synonyms: 1-Methylimidazole-2(3H)-thioneCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2A6 Inhibitors
  5. Drug

    Hydroxyethyl ethylcellulose

    go.drugbank.com/drugs/DB14139
    Approved

    Hydroxyethyl ethylcellulose modulates bacterial binding to salivary pellicle; moderately effective in preventing plaque formation.

    Synonyms: 2-hydroxyethyl ether of ethyl cellulose, Ethyl-2-hydroxyethylcelluloseCategories: Compounds used in a research, industrial, or household setting
  6. Pathway

    Capreomycin Action Pathway

    smpdb.ca/view/SMP0126284
    Drug action

    It binds to the 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA. With this binding, the 16S rRNA can't interact with the 23S rRNA, this inhibits the translocation during the peptide elongation. … Also, this drug affects protein synthesis by stabilizing the peptidyl-tRNA complex in the pretranslocation complex.

    Drugs: Capreomycin
    Enzymes: 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA
  7. Pathway

    Azithromycin Action Pathway

    smpdb.ca/view/SMP0126739
    Drug action

    Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration. It is commonly administered via oral consumption and diffuses throughout the body. It is primarily used for the treatmen...

    Drugs: Azithromycin
    Enzymes: 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA
  8. Pathway

    Erythromycin Anti-Bacterial Action Pathway

    smpdb.ca/view/SMP0126741
    Drug action

    Erythromycin should be taken on an empty stomach at least 30 minutes to 2 hours prior to a meal in order to increase absorption. Products that contain grapefruit should be avoided.

    Drugs: Erythromycin
    Enzymes: 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA
  9. Drug

    RG-7795

    go.drugbank.com/drugs/DB06329
    Investigational

  10. Drug

    Oxilofrine

    go.drugbank.com/drugs/DB11610
    Approved

    Oxilofrine is used in combination with [DB11609] as an antitussive. It is currently marketed in Canada by Valeant under the tradename Cophylac.

    Synonyms: 4-HMP, 4-hydroxyephedrine