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Displaying results 4541 - 4550 of 10000 in total
  1. Drug

    Zinc citrate

    go.drugbank.com/drugs/DB11154
    ApprovedInvestigational

    Zinc citrate is a zinc salt of citric acid. It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element.

    Mixtures: Corvite 150, Cal-mag Complete With Zinc, C and DProducts: Zinc 50 mg
  2. Drug

    Carboprost tromethamine

    go.drugbank.com/drugs/DB00429
    ApprovedInvestigational

    A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.

    Synonyms: 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium (5Z,9α,11β,13E,15S)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1-oate, 15(S)-15-methyl-PGF2α tromethamine saltCategories: Prostaglandins F, Synthetic
  3. Drug

    Thiamphenicol

    go.drugbank.com/drugs/DB08621
    Investigational

    Products: URFAMYCİN ENJEKTABL FLAKON 500 MG, 1 FLAKON + 1 AMPUL, URFETEM 750 MG FLAKON (1 FLAKON)
  4. Drug

    Dapoxetine

    go.drugbank.com/drugs/DB04884
    Investigational

    In October 2005, the company received a FDA Non-Approvable letter from the FDA, at which time they planned to work with regulators to address outstanding questions. … In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo.

    Mixtures: DAPOXIL 30/50 MG FILM KAPLI TABLET,18 FILM KAPLI TABLET, DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  5. Drug

    Crizotinib

    go.drugbank.com/drugs/DB08865
    ApprovedInvestigational

    Crizotinib is a tyrosine kinase receptor inhibitor used for the treatment of anaplastic lymphoma kinase (ALK) or ROS1-positive non-small cell lung cancer (NSCLC) tumors, as well as ALK-positive anaplastic … [L42460] By targeting the echinoderm microtubule-associated protein-like 4 (EML4)-ALK fusion protein, crizotinib offers robust effectiveness in treating NSCLC in patients with this type of rearrangement

    Synonyms: (R)-crizotinibCategories: Heterocyclic Compounds, 1-Ring, Organic Cation Transporter 1 Inhibitors
  6. Drug

    Mifamurtide

    go.drugbank.com/drugs/DB13615
    ApprovedInvestigational

    5-year event-free survival. … In the US, it is currently under investigation that holds orphan drug status for the treatment of osteosarcoma [A31746].

    Products: MEPACT 4 MG INFÜZYONLUK DISPERSIYON KONSANTRESI IÇIN TOZ ,FLAKON, 1 ADET, MEPACT® POLVO PARA CONCENTRADO PARA DISPERSIÓN PARA PERFUSIÓN
  7. Target

    Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A

    go.drugbank.com/bio_entities/BE0003558
    TargetHumans

    Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively (PubMed:10725373, PubMed:10906126, PubMed:11050148)

    Polypeptides: Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AFunction: 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
  8. Target

    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

    go.drugbank.com/bio_entities/BE0000243
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The ...

    Polypeptides: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
  9. Target

    5'-AMP-activated protein kinase catalytic subunit alpha-1

    go.drugbank.com/bio_entities/BE0000677
    TargetHumans

    Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:17307971, PubMed:17712357, PubMed:24563466, PubMed:31492851, PubMed:37821951...

    Polypeptides: 5'-AMP-activated protein kinase catalytic subunit alpha-1
  10. Target

    tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase

    go.drugbank.com/bio_entities/BE0002518
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

    Polypeptides: tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase