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Displaying results 4551 - 4560 of 7604 in total
  1. Drug

    Propiomazine

    go.drugbank.com/drugs/DB00777
    Approved

    Structurally and pharmacologically similar to clozapine, propiomazine binds to alpha(1), dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors. … Propiomazine, an atypical antipsychotic agent, is used to treat both negative and positive symptoms of schizophrenia, acute mania with bipolar disorder, agitation, and psychotic symptoms in dementia.

  2. Drug

    Phenformin

    go.drugbank.com/drugs/DB00914
    ApprovedWithdrawn

    A biguanide hypoglycemic agent with actions and uses similar to those of metformin. … Although it is generally considered to be associated with an unacceptably high incidence of lactic acidosis, often fatal, it is still available in some countries.

  3. Drug

    Calusterone

    go.drugbank.com/drugs/DB01564
    ExperimentalIllicit

    A 17-alkylated orally active androgenic steroid. A Schedule IV drug in Canada.

  4. Drug

    Dexamethasone isonicotinate

    go.drugbank.com/drugs/DB11487
    ExperimentalVet approved

    Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally.

  5. Drug

    Tomligisiran

    go.drugbank.com/drugs/DB19330
    Investigational

    Tomligisiran is under investigation in clinical trial NCT06537414 (A Study of Sequential Therapy With Daplusiran/tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis

    Synonyms: -9-YL))DA), 3'-(O-(CIS-4-((3S,8S)-17-((2-(ACETYLAMI, RNA, ((1'-DE(6-AMINO-9H-PURIN-9-YL))DA-(5'->5')-CM-GM-CM-UM-GM-UM-AM-GM-(2'-DEOXY-2'-FLUORO)G-(2'-DEOXY-2'-FLUORO)C-(2'-DEOXY-2'-FLUORO)A-UM-AM-AM-AM-UM-UM-GM-GM-UM-AM-(3'->3')-SP-(1'-DE(6-AMINO-9H-PURIN
  6. Drug

    Daplusiran

    go.drugbank.com/drugs/DB19331
    Investigational

    Daplusiran is under investigation in clinical trial NCT06537414 (A Study of Sequential Therapy With Daplusiran/tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis

    Synonyms: -2'-FLUORO)G-UM-(2'-DEOXY-2'-FLUORO)C-CM-AM-SP-CM),, RNA, (AM-SP-(2'-DEOXY-2'-FLUORO)G-SP-AM-SP-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY-2'-FLUORO)A-UM-(2'-DEOXY-2'-FLUORO)U-GM-(2'-DEOXY-2'-FLUORO)A-GM-(2'-DEOXY-2'-FLUORO)A-GM-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY
  7. Drug

    Tyloxapol

    go.drugbank.com/drugs/DB06439
    ApprovedInvestigational

    Tyloxapol is a non-ionic detergent often used as a surfactant.

  8. Drug

    Calcium phosphate dihydrate

    go.drugbank.com/drugs/DB14481
    Approved

  9. Drug

    Davesomeran

    go.drugbank.com/drugs/DB17091
    ApprovedInvestigational

    Similar to the previous Moderna COVID-19 vaccine, Moderna Bivalent vaccine encodes the full-length pre-fusion stabilized spike (S) protein to elicit an immune response. … [L43882] On November 3rd 2022, Health Canada also approved the Moderna Bivalent Vaccine as a booster shot in individuals 18 years of age or older.[L43862]

  10. Drug

    PEG-uricase

    go.drugbank.com/drugs/DB05321
    Investigational

    PEG-uricase, a polyethylene glycol ("PEG") conjugate of recombinant porcine uricase (urate oxidase), which breaks down the uric acid deposits is being studied in Phase III clinical trials for the treatment of severe, treatment-refractory...