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Prothrombin
go.drugbank.com/drugs/DB11311ApprovedInvestigationalProthrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with
Mixtures: Beriplex P/n 500, Beriplex P/n 1000Serotonin
go.drugbank.com/drugs/DB08839InvestigationalNutraceuticalNot evaluated by the FDA, homeopathic product.
Categories: Heterocyclic Compounds, 2-Ring, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: 3-(2-Aminoethyl)-1H-indol-5-ol, 5-HTCilomilast
go.drugbank.com/drugs/DB03849InvestigationalFollowing four clinical trials, the drug proved to be effective in treating COPD, however it has never been marketed due to a poor side effect profile. … Cilomilast (Ariflo, SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD).
Categories: Phosphodiesterase 4 InhibitorsSynonyms: cis-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acidPiclidenoson
go.drugbank.com/drugs/DB05511InvestigationalIt is also being considered for the treatment of other autoimmune-inflammatory disorders, such as Crohn's disease, psorasis and dry eye syndrome. … CF101 is supplied as an oral drug and has an excellent safety profile.
Categories: Heterocyclic Compounds, 2-RingHuman calcitonin
go.drugbank.com/drugs/DB06773Approved[A32099] It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus metabolism. … Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect.
Opipramol
go.drugbank.com/drugs/DB12930InvestigationalOpipramol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
Categories: Heterocyclic Compounds, 3-Ring, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromePerhexiline
go.drugbank.com/drugs/DB01074ApprovedPerhexiline is a coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingAllogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15731InvestigationalORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord. … Regarding the modifications of these UC-MSCs, CD362, also known as syndecan-2, is a surface marker identified on MSCs with enhanced clonogenicity and immunomodulatory properties.
Synonyms: ORBCEL C™, Orbcel-CRaltitrexed
go.drugbank.com/drugs/DB00293ApprovedInvestigationalRaltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingProducts: TOMUDEX ® 2 MG, TOMUDEX 2 MG FLAKON, 1 ADETReglitazar
go.drugbank.com/drugs/DB04971ExperimentalReglitazar, an isoxazolidine-3,5-dione derivative, is being developed by Pfizer for the treatment of diabetes. It is the first non-thiazolidenedione to enter clinical trials.
Categories: Heterocyclic Compounds, 1-Ring