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Displaying results 451 - 460 of 10000 in total
  1. Target

    Leucine-rich repeat-containing G protein-coupled receptor 5

    go.drugbank.com/bio_entities/BE0010835
    TargetHumans

    Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle.

    Polypeptides: Leucine-rich repeat-containing G protein-coupled receptor 5Synonyms: G protein-coupled receptor 49, G protein-coupled receptor 67
  2. Drug

    Metipranolol

    go.drugbank.com/drugs/DB01214
    ApprovedWithdrawn

    A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.

  3. Drug

    Dextropropoxyphene

    go.drugbank.com/drugs/DB00647
    ApprovedIllicitWithdrawn

    Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe and the United States. … The drug is often referred to as the general form, "propoxyphene", however only the dextro-isomer (dextropropoxyphene) has any analgesic effect.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  4. Drug

    Bimatoprost

    go.drugbank.com/drugs/DB00905
    ApprovedInvestigational

    It has the ability to reduce ocular hypotension, proving effective in conditions such as ocular hypertension and glaucoma. … Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form.

    Mixtures: BIMAPROS T, BEMATORİN-T 0,3 MG + 5 MG/1 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADETSynonyms: (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide
  5. Drug

    Methylphenobarbital

    go.drugbank.com/drugs/DB00849
    Approved

    A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.

  6. Drug

    Cupric oxide

    go.drugbank.com/drugs/DB11134
    Approved

    Cupric oxide may be found in over-the-counter vitamin-mineral supplements as a source of [DB09130]. The mean daily dietary intake of copper in adults ranges between 0.9 and 2.2 mg [L2422]. … Cupric oxide, or copper (II) oxide, is an inorganic compound with the chemical formula CuO.

    Mixtures: TL-Folate, RE Nata OB
  7. Drug

    Ciclesonide

    go.drugbank.com/drugs/DB01410
    ApprovedInvestigational

    Ciclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.

    Categories: Agents to Treat Airway Disease
  8. Drug

    Encainide

    go.drugbank.com/drugs/DB01228
    ApprovedWithdrawn

    Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack. … The manufacturer of Enkaid capsules voluntarily withdrew the product from the US market on December 16, 1991.

  9. Indication

    Deficiency of the interleukin-1 receptor antagonist

    go.drugbank.com/conditions/DBCOND0008480
    Drugs: Anakinra · Rilonacept
    Synonyms: Deficiency of interleukin-1 receptor antagonist, Interleukin-1 receptor antagonist deficiency
  10. Drug

    Riboflavin

    go.drugbank.com/drugs/DB00140
    ApprovedInvestigationalNutraceuticalVet approved

    The richest natural source is yeast. … It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide.

    Mixtures: Folika-T, TL-Folate