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Displaying results 451 - 460 of 3732 in total
  1. Target

    Macrophage receptor MARCO

    go.drugbank.com/bio_entities/BE0009001
    TargetHumans

    Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria (PubMed:9468508).

    Polypeptides: Macrophage receptor MARCOSynonyms: Scavenger receptor class A member 2, Macrophage receptor with collagenous structure
  2. Target

    Histamine H1 receptor

    go.drugbank.com/bio_entities/BE0009144
    CarrierTargetMouse

    In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well ...

    Polypeptides: Histamine H1 receptor
  3. Target

    Dopamine receptor D2

    go.drugbank.com/bio_entities/BE0009377
    TargetRat

    Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (PubMed:1321233).

    Polypeptides: Dopamine receptor D2Synonyms: Dopamine D2 receptor, D(2) dopamine receptor
  4. Target

    Melanocortin receptor 3

    go.drugbank.com/bio_entities/BE0009683
    TargetHumans

    G protein-coupled receptor for melanocyte-stimulating hormones (alpha, beta, and gamma-MSH) and corticotropin/ACTH, which are peptide products of the POMC precursor (PubMed:37524700, PubMed:8463333).

    Polypeptides: Melanocortin receptor 3Function: corticotropin receptor activity
  5. Target

    Asialoglycoprotein receptor 1

    go.drugbank.com/bio_entities/BE0010188
    TargetCarrierTransporterHumans

    Upon ligand binding, the receptor-ligand complex is internalized and trafficked to a sorting organelle, where dissociation occurs. The receptor is then recycled back to the cell surface

    Polypeptides: Asialoglycoprotein receptor 1Function: asialoglycoprotein receptor activity
  6. Target

    GABA(B) Receptor

    go.drugbank.com/bio_entities/BE0010194
    Target

    Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating … Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating

    Polypeptides: Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2Synonyms: GABA-B receptor 1, GABA-B receptor 2
  7. Target

    Interleukin-21 receptor

    go.drugbank.com/bio_entities/BE0010657
    TargetHumans

    This is a receptor for interleukin-21

    Polypeptides: Interleukin-21 receptorSynonyms: IL-21 receptor, Novel interleukin receptor
  8. Target

    Neuromedin-B receptor

    go.drugbank.com/bio_entities/BE0013104
    TargetHumans

    Receptor for neuromedin-B (PubMed:1655761). … Plays a role in CSF1-induced proliferation of osteoclast precursors by contributing to the positive regulation of the expression of the CSF1 receptor CSF1R (By similarity)

    Polypeptides: Neuromedin-B receptorSynonyms: Neuromedin-B-preferring bombesin receptor
  9. Target

    Interleukin-23 receptor

    go.drugbank.com/bio_entities/BE0015564
    TargetHumans

    Associates with IL12RB1 to form the interleukin-23 receptor.

    Polypeptides: Interleukin-23 receptorSynonyms: IL-23 receptor
  10. Target

    Discoidin domain receptor

    go.drugbank.com/bio_entities/BE0027487
    TargetHumans

    It functions as a cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. … Tyrosine kinase that functions as a cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation

    Polypeptides: Discoidin domain-containing receptor 2, Epithelial discoidin domain-containing receptor 1Synonyms: Discoidin domain receptor 2, Discoidin receptor tyrosine kinase