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Acenocoumarol
go.drugbank.com/drugs/DB01418ApprovedInvestigationalAcenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. … This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation.
Categories: 4-Hydroxycoumarins, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 4-Hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-2H-1-benzopyran-2-one, 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-oneAntrafenine
go.drugbank.com/drugs/DB01419ApprovedAntrafenine is a piperazine derivative drug that acts as an analgesic and anti-inflammatory drug with similar efficacy to naproxen.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingTestosterone propionate
go.drugbank.com/drugs/DB01420ApprovedInvestigationalVet approvedWithdrawnTestosterone propionate is a slower-releasing anabolic steroid with a short half-life. … [T83] Testosterone propionate was developed initially by Watson labs, and FDA approved on February 5, 1974.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesOxybenzone
go.drugbank.com/drugs/DB01428ApprovedIt is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays. … It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents.
Mixtures: Beauticontrol Sunlogics O-F Tan.mist SPF 8, OBAGI-C RX SYSTEM C-EXFOLIATING DAY with Vitamin CCategories: Compounds used in a research, industrial, or household settingAllylestrenol
go.drugbank.com/drugs/DB01431InvestigationalA synthetic steroid with progestational activity.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 17α-allylestr-4-en-17β-ol, 3-deketo-17α-allyl-19-nortestosteroneMethadyl acetate
go.drugbank.com/drugs/DB01433ExperimentalIllicitA narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence.
gamma-Hydroxybutyric acid
go.drugbank.com/drugs/DB01440ApprovedIllicitInvestigationalToday Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem falls under penalties of Schedule I. … It is used illegally under the street names Juice, Liquid Ecstasy or simply G, either as an intoxicant, or as a date rape drug.
Synonyms: 4-hydroxybutanoate, 3-carboxypropoxy acidBufotenine
go.drugbank.com/drugs/DB01445ExperimentalIllicitBufotenin has been used as a tool in CNS studies and misused as a psychedelic. … A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics.
Categories: N,N-Dimethyltryptamine, Heterocyclic Compounds, 2-RingSynonyms: 3-[2-(dimethylamino)ethyl]-5-indolol, 3-[2-(dimethylamino)ethyl]indol-5-olIndopan
go.drugbank.com/drugs/DB01446ExperimentalIllicitIt was developed in the 1960's by Upjohn with the intention for use as an antidepressant. In the 1990's, indopan became regulated as a Schedule I controlled substance in the United states. … Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 2-RingSynonyms: 1-(1H-Indol-3-yl)-2-propanamine, 3-(2-Aminopropyl)indoleMidomafetamine
go.drugbank.com/drugs/DB01454IllicitInvestigationalAn N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. … It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSynonyms: 3, 4-Methylenedioxymethamphetamine