Search
Baclofen
go.drugbank.com/drugs/DB00181ApprovedInvestigationalBaclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasti...
Synonyms: DL-4-Amino-3-p-chlorophenylbutanoic acid, DL-BaclofenInternational brands: Nu-BaclofenSuccinylcholine
go.drugbank.com/drugs/DB00202ApprovedInvestigationalSuccinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter acetylcholine (ACh) linked by their acetyl groups. It has been widely used for over 50 years, most commonly in its ...
Products: Cloruro de suxametonioAmiodarone
go.drugbank.com/drugs/DB01118ApprovedInvestigationalAmiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpat...
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: AMIODARONE PH&T, Nu-amiodaroneGalantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigationalas mild cognitive impairment, cognitive impairment in schizophrenia and bipolar disorder, and autism; however, re-development of the drug for Alzheimer’s disease did not commence until the early 1990s due
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: REMINYL ®ER CAPSULAS DE 8 MG, REMINYL ® ER CAPSULAS DE 16 MGMoxifloxacin
go.drugbank.com/drugs/DB00218ApprovedInvestigationalMoxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for ...
Mixtures: Dex-Moxi PF, DexMoxiKetor PFCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsFentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approvedFentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. … [L6748] Opioid overdoses kill an average of 11 Canadians daily.[L6751] Fentanyl was FDA approved in 1968.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613]
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: DUROGESIC D-TRANS, CITRATO DE FENTANILO 0.05MG/MLTreprostinil
go.drugbank.com/drugs/DB00374ApprovedInvestigationalHowever, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room temperature.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: TREPROSTINIL DR. REDDY'SAcemetacin
go.drugbank.com/drugs/DB13783ApprovedInvestigationalAcemetacin is a carboxymethyl ester of indometacin. It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin. In clinical...
Products: RANTUDIL ® LP 90 MG CAPSULAS DE LIBERACIÓN PROLONGADANorepinephrine
go.drugbank.com/drugs/DB00368ApprovedInvestigationalPrecursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse project...
Products: Levophed Injection 4mg/4ml VialAcetaminophen
go.drugbank.com/drugs/DB00316ApprovedInvestigational[L5783] Due to the possibility of fatal overdose and liver failure associated with the incorrect use of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines
Synonyms: p-acetamidophenol, p-acetaminophenolInternational brands: Oraphen-PD