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Volanesorsen
go.drugbank.com/drugs/DB15067Approved[L16621] This drug is not commonly prescribed as it is used as an adjunct to diet in patients at high risk for pancreatitis, who have had inadequate response to triglyceride lowering therapy. … Volanesorsen is an antisense oligonucleotide that binds to apoC-III mRNA to prevent its translation.
Vepdegestrant
go.drugbank.com/drugs/DB19006ApprovedInvestigational[A275507, A275509] It serves as an advanced option to address the clinical challenge of endocrine-resistant breast cancer subtypes. … [A275507, A275508, A275511] It was identified through a targeted medicinal chemistry optimization campaign to act as a next-generation endocrine therapy for breast cancer.
Bromazepam
go.drugbank.com/drugs/DB01558ApprovedIllicitOne of the benzodiazepines that is used in the treatment of anxiety disorders. It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances.
Products: BROMAZEPAM DOC GENERICI, BROMAZEPAM MYLAN GENERICSPirfenidone
go.drugbank.com/drugs/DB04951ApprovedInvestigational[A251365] The FDA first approved pirfenidone alongside [nintedanib] as one of the first drugs to treat IPF.[A251165] … [A251370] While its mechanism of action is not yet fully understood, pirfenidone is proposed to primarily regulate tumor necrosis factor (TNF) pathways and modulate cellular oxidation.
Camphor
go.drugbank.com/drugs/DB01744ApprovedInvestigationalWithdrawnThe FDA ruled that camphorated oil could not be marketed in the United States and that no product could contain a concentration higher than 11%.
Mixtures: Wok Lok Pain Relieving Oil, Wok Lok Pain Relieving OilSynonyms: (+)-bornan-2-oneGlycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[L33110] It is one of the most commonly prescribed anticholinergic medications. … Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers.[L33110] They are both quaternary ammonium compounds and long acting muscarinic antagonists.
Bupropion
go.drugbank.com/drugs/DB01156ApprovedInvestigational[A178804,A178807] When used as an aid to smoking cessation, bupropion is thought to confer its anti-craving and anti-withdrawal effects by inhibiting dopamine reuptake, which is thought to be involved … [A6399,A178840] Lack of activity at these receptors results in a more tolerable side effect profile; bupropion is less likely to cause sexual side effects, sedation, or weight gain as compared to SSRIs
Manganese cation
go.drugbank.com/drugs/DB06757ApprovedInvestigationalNutraceuticalManganese is a transition metal that was first described in the 19th and 20th centuries. It is environmentally abundant, being the fifth most abundant metal and the twelfth most abundant element overall on Earth. Manganese intake primari...
Mixtures: One A Day Multiple Vit W Minerals, Vege Swiss One Multivitamin W Chel Mins TabElacestrant
go.drugbank.com/drugs/DB06374ApprovedInvestigational[L49334] Elacestrant binds to estrogen receptor-alpha (ERα) and acts as a selective estrogen receptor degrader (SERD) thanks to its ability to block the transcriptional activity of the ER and promote … [A256828,A256863,L44948] Other types of endocrine therapy, such as selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs), may lead to drug resistance over time; therefore, the use
Pepsin
go.drugbank.com/drugs/DB13198ApprovedWithdrawnStudies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated egg whites to dissolve. … Soon afterward, it was shown that these protein nutrients were cleaved by pepsin to products called _peptones_ [A32603].
Mixtures: Glutamic Acid HCl Betaine HCl W Pepsin