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Displaying results 4601 - 4610 of 10000 in total
  1. Drug

    Medroxyprogesterone acetate

    go.drugbank.com/drugs/DB00603
    ApprovedInvestigational

    Medroxyprogesterone acetate (MPA) is a [progesterone] derivative that is more resistant to metabolism for improved pharmacokinetic properties.

    Mixtures: DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADET, DIVICONT TABLETAS 1 MG/5 MGCategories: Pregnen (4) Derivatives, P-glycoprotein inhibitors
  2. Drug

    Taurolidine

    go.drugbank.com/drugs/DB12473
    ApprovedInvestigational

    It is a derivative of the amino acid [taurine]. … and Antifungal Drugs (LPAD pathway) for the prevention of catheter-related bloodstream infections in a limited and specific patient population.

    Categories: Heterocyclic Compounds, 1-RingProducts: Taurolin (Taurolidin "Geistlich") 2% - Instillationslösung
  3. Drug

    Reteplase

    go.drugbank.com/drugs/DB00015
    ApprovedInvestigationalWithdrawn

    Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains the activity-related kringle-2 and serine protease domains of human tPA. … Three domains are deleted from retavase - kringle-1, finger, and epidermal growth factor (EGF).

    Synonyms: Human t-PA (residues 1-3 and 176-527)Products: RAPILYSIN 10 U IV ENJ. ICIN STERIL LIYOFILIZE TOZ ICEREN FLAKON, 2 ADET
  4. Indication

    Grade 1, grade 2, grade 3, grade 4 Urinary Tract Infection

    go.drugbank.com/conditions/DBCOND0128761
    Drugs: Amikacin · Cycloserine · Tetracycline
    Synonyms: Grade 1, grade 2, grade 3, grade 4 Urinary Tract Infection
  5. Indication

    Mucopolysaccharidosis Type II (MPS II)

    go.drugbank.com/conditions/DBCOND0065668
    Drugs: Idursulfase · Tividenofusp alfa
    Synonyms: MPS 2 - Mucopolysaccharidosis 2, Mucopolysaccharidosis Type 2
  6. Drug

    Crisaborole

    go.drugbank.com/drugs/DB05219
    ApprovedInvestigational

    This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 years old and older. … Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis.

    Categories: Cytochrome P-450 CYP2B6 Inhibitors, Phosphodiesterase 4 InhibitorsProducts: Staquis Topical Ointment 2%
  7. Indication

    Myasthenia Gravis

    go.drugbank.com/conditions/DBCOND0028961
    Drugs: Distigmine · Ephedrine · Neostigmine · Pyridostigmine · Zilucoplan
    Synonyms: MG - Myasthenia gravis
  8. Target

    Actin-related protein 2/3 complex subunit 2

    go.drugbank.com/bio_entities/BE0004252
    TargetHumans

    Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin ...

    Polypeptides: Actin-related protein 2/3 complex subunit 2
  9. Drug

    Human immunoglobulin G

    go.drugbank.com/drugs/DB00028
    ApprovedInvestigational

    Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation.

    Categories: Immunoglobulin G, Human Immunoglobulin GSynonyms: Human immunoglobulin G, Immunoglobulin G, human
  10. Drug

    Tripelennamine

    go.drugbank.com/drugs/DB00792
    ApprovedVet approved

    A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications.

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2D6 InhibitorsProducts: Vaginex W Tripelennamine Crm 2%, Vagin-X