Search

Displaying results 4611 - 4620 of 10000 in total
  1. Drug

    Bromopyruvate

    go.drugbank.com/drugs/DB17135
    Experimental

    Categories: Compounds used in a research, industrial, or household setting, Pyruvate Dehydrogenase Complex, antagonists & inhibitors
  2. Drug

    Malachite Green

    go.drugbank.com/drugs/DB03895
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Indole-3-Glycerol Phosphate

    go.drugbank.com/drugs/DB04143
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    ABT-510

    go.drugbank.com/drugs/DB05434
    Investigational

    ABT-510 is a peptide mimetic of thrombospondin-1 (TSP-1), blocks angiogenesis in vitro and in vivo, and slows tumor growth.

  5. Drug

    Demeclocycline

    go.drugbank.com/drugs/DB00618
    Approved

    A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.

  6. Drug

    Cirazoline

    go.drugbank.com/drugs/DB09202
    Experimental

    Cirazoline has also been shown to decrease food intake in rats, purportedly through activation of α1-adrenoceptors in the paraventricular nucleus in the hypothalamus of the brain. … Cirazoline acts on a number of α adrenergic receptors. It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2.

  7. Drug

    Human Interleukin 8

    go.drugbank.com/drugs/DB16456
    Investigational

    Interleukin-8 is under investigation in clinical trial NCT05148234 (BMS-986253 in Myelodysplastic Syndromes).

  8. Drug

    BOS172722

    go.drugbank.com/drugs/DB15498
    Investigational

    The key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment, as its inhibition could lead to favorable effects. … [A187120] An in vivo study combined BOS172722 with [Paclitaxel] for the treatment of triple hormone receptor negative breast cancer, and demonstrated promising synergistic effects.[A187123]

  9. Drug

    ISIS 325568

    go.drugbank.com/drugs/DB06099
    Investigational

    It was under investigation in clinical trial NCT00519727 (Safety Study of ISIS 325568 in Healthy Volunteers) for lowering blood glucose and helping control type 2 diabetes.

  10. Drug

    KOS-1584

    go.drugbank.com/drugs/DB05903
    Investigational

    Epothilones are anticancer agents with a taxane-like mechanism of action that have demonstrated activity in taxane-resistant tumors.

    Synonyms: (E)-9,10-Dehydroepothilone D, (E)-9,10-Didehydroepothilone D