Search
Imexon
go.drugbank.com/drugs/DB05003InvestigationalImexon is currently being studied for the treatment of pancreatic, lung, breast, prostate, melanoma, and multiple myeloma cancers. It belongs to the family of drugs called cyanoaziridine derivatives. … Imexon is a cyanoaziridine derivative. Imexon is a thiol-binding small molecule which induces mitochondrial oxidation, a loss of membrane potential and cytochrome C, leading to apoptosis.
Taurochenodeoxycholic acid
go.drugbank.com/drugs/DB08833ExperimentalAs a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to … Taurochenodeoxycholic acid is an experimental drug that is normally produced in the liver. Its physiologic function is to emulsify lipids such as cholesterol in the bile.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesUric acid
go.drugbank.com/drugs/DB08844InvestigationalUric acid is the last product of purine metabolism in humans. The formation of uric acid is through the enzyme xanthine oxidase, which oxidizes oxypurines. … Normally a small amount of uric acid is present in the body, but when there is an excess amount in the blood, called hyperuricemia, this can lead to gout and formation of kidney stones.
Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingDuvakitug
go.drugbank.com/drugs/DB19444InvestigationalDuvakitug is under investigation in clinical trial NCT05668013 (A Study to Evaluate the Long-term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease).
Synonyms: Immunoglobulin G1 [de-449-lysine], anti-(human tumor necrosis factor superfamily protein TNFSF15) (human monoclonal TEV-48574 γ1-chain), disulfide with human monoclonal TEV-48574 λ-chain, dimer, gamma1 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV1-8*01 (92.9%) -(IGHD) -IGHJ4*01 (92.9%),CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119)-Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3Camazepam
go.drugbank.com/drugs/DB01489ExperimentalIllicitCamazepam is also believed to increase attention, and is associated with skin disorders. In the United States camazepam is regulated as a Schedule IV controlled substance. … Camazepam also has less side effects, such as impaired cognition and reaction times, compared to other benzodiazepines.
Categories: Heterocyclic Compounds, 2-RingCilomilast
go.drugbank.com/drugs/DB03849InvestigationalFollowing four clinical trials, the drug proved to be effective in treating COPD, however it has never been marketed due to a poor side effect profile. … Cilomilast (Ariflo, SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD).
Synonyms: cis-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acidCategories: Phosphodiesterase 4 InhibitorsPosizolid
go.drugbank.com/drugs/DB04850InvestigationalIn July 2002, after completion of phase I trials in December 2001, AstraZeneca announced that they were no longer pursuing the development of Posizolid, presumably due to negative trial results (though … Posizolid (AZD2563) is an oxazolidinone antibiotic.
Categories: Heterocyclic Compounds, 1-RingAmcinonide
go.drugbank.com/drugs/DB00288ApprovedAmcinonide is a corticosteroid.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersLynestrenol
go.drugbank.com/drugs/DB12474ApprovedWithdrawnLynestrenol is a progestin and prodrug of [norethisterone].
Categories: Sex Hormones and Modulators of the Genital System, Cytochrome P-450 SubstratesProducts: ORGAMETRİL 5 MG TABLET, 30 ADETTenocyclidine
go.drugbank.com/drugs/DB01520IllicitInvestigationalIt is more potent than phencyclidine and hence, this drug was classified under the schedule 1 in 1970. … Tenocyclidine (TCP, thienyl cyclohexylpiperidine) is a dissociative anesthetic drug with stimulant and hallucinogenic effects.
Synonyms: 1-[1-(thiophen-2-yl)cyclohexyl]piperidineCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting