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SO-101
go.drugbank.com/drugs/DB05345ExperimentalSO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected for its use in insomnia. Doxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages ty...
HLX70
go.drugbank.com/drugs/DB16509InvestigationalHLX70, a recombinant humanized anti-S protein monoclonal antibody intended for intravenous infusion, was under investigation in clinical trials NCT05429385 and NCT04561076 to evaluate its safety and pharmacokinetics in healthy adult volu...
PYM50018
go.drugbank.com/drugs/DB05126ExperimentalIt is developed for the treatment of amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).
SYNB1020
go.drugbank.com/drugs/DB17667InvestigationalIt was initially designed to convert ammonia to L-arginine [A258838] and granted orphan designation by the FDA for the treatment of urea cycle disorders in August 2016;[L45988] however, the manufacturer
Triazavirin
go.drugbank.com/drugs/DB15622Investigational[A191709,A191625,A191916] It appears that Triazavirin has shown promise in reducing influenza disease severity and associated complications.
Ceramide NP
go.drugbank.com/drugs/DB14111InvestigationalIt is widely used as a moisturizer in various cosmetic and personal products. Together with ceramide 1, they synergistically improve the skin barrier function in humans [A27232, A27233].
Sugemalimab
go.drugbank.com/drugs/DB16641ApprovedInvestigationalL32868, L32873, L53333, L53388] This drug is the first PD-L1 antibody which naturally lacks antibody-dependent cell-mediated cytotoxicity/complement-dependent cytotoxicity (ADCC/CDC) activity which allows it
Technetium Tc-99m ciprofloxacin
go.drugbank.com/drugs/DB05488Experimental99mTc-Ciprofloxacin is a new formulation of ciprofloxacin (INFECTON), being investigated as a radioimaging agent for the potential diagnosis of infection, including fever of unknown origin, osteomyelitis, wound infection, abdominal absce...
Relugolix
go.drugbank.com/drugs/DB11853ApprovedInvestigationalIt was first approved in Japan in 2019, under the brand name Relumina, for the symptomatic treatment of uterine fibroids,[A225816] and more recently by the United States' FDA in 2020, under the brand name
Sotagliflozin
go.drugbank.com/drugs/DB12713ApprovedInvestigational[L39734] A similar approval has also been sought in the US, but the FDA has since published a proposal to refuse the approval because the data submitted did not show that it was safe under the proposed