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Domiphen
go.drugbank.com/drugs/DB11594ApprovedDomiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered antiseptic agent.
Mixtures: Mouthwash and Gargle, Lander Orl Hygienic Mwh and GargleCategories: Alimentary Tract and Metabolism, Antiinfectives and Antiseptics for Local Oral TreatmentTiludronic acid
go.drugbank.com/drugs/DB01133ApprovedVet approvedWithdrawnTiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to [etidronic acid] and [clodronic acid]. … [A1923] Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone.[A202235] Tiludronic acid was granted FDA approval on 7 March 1997.[L4763]
Categories: Drugs Affecting Bone Structure and MineralizationAlmotriptan
go.drugbank.com/drugs/DB00918ApprovedIt works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that cause pain, nausea, and other symptoms … Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists.
Categories: Serotonin-1b and Serotonin-1d Receptor AgonistCarbonic anhydrase 1
go.drugbank.com/bio_entities/BE0000267TargetEnzymeCarrierHumansCan hydrate cyanamide to urea (PubMed:10550681)
Synonyms: CAB, CA-ICarbonic anhydrase 2
go.drugbank.com/bio_entities/BE0000322TargetEnzymeCarrierHumansEssential for bone resorption and osteoclast differentiation (PubMed:15300855). Involved in the regulation of fluid secretion into the anterior chamber of the eye. … Can also hydrate cyanamide to urea (PubMed:10550681, PubMed:11015219). Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (PubMed:15990874).
Synonyms: CAC, CA-IIPicolinic acid
go.drugbank.com/drugs/DB05483ExperimentalIt acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of tryptophan. … Picolinic acid has been shown to be an anti-viral in vitro and in vivo, and sometimes works in conjunction with other cytokines such as interferon gamma to affect immune responses.
Categories: Compounds used in a research, industrial, or household settingDimethylthiambutene
go.drugbank.com/drugs/DB01444ExperimentalIllicitDimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid analgesic drug. … It is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs 1961, presumably due to high abuse potential, although little more information is available.
Synonyms: N,N,1-trimethyl-3,3-di-2-thienylallylamine, N,N-dimethyl-4,4-di(2-thienyl)-3-buten-2-amineFerrous succinate
go.drugbank.com/drugs/DB14489ApprovedInvestigationalCategories: Blood and Blood Forming OrgansLumefantrine co-artemether
go.drugbank.com/drugs/DB13085ApprovedInvestigationalWithdrawnThe exact mechanism of action of lumefantrine is not well defined, but it is thought to inhibit -hematin formation, an important detoxification pathway for the parasite. … The combination is an effective and well-tolerated malaria treatment, providing high cure rates even in areas of multi-drug resistance.