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Displaying results 4651 - 4660 of 10000 in total
  1. Drug

    Chlorothiazide

    go.drugbank.com/drugs/DB00880
    ApprovedInvestigationalVet approved

    A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)

    Synonyms: 6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide, 6-chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxideCategories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Risedronic acid

    go.drugbank.com/drugs/DB00884
    ApprovedInvestigational

    Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].

    Mixtures: RISEPLUS TEDAVI PAKETİ, 4+24 ADET, RISEFIX COMBI TEDAVI PAKETI, 4+24 ADETCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Remifentanil

    go.drugbank.com/drugs/DB00899
    ApprovedInvestigational

    Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. … Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.

    Categories: Heterocyclic Compounds, 1-RingProducts: ULTIVA 1 MG ENJEKTABL TOZ İÇEREN FLAKON, 5 ADET, REMIFENTANIL B. BRAUN
  4. Drug

    Didanosine

    go.drugbank.com/drugs/DB00900
    ApprovedInvestigational

    A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. … Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative

    Synonyms: 9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one, 9-((2S,5R)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-olCategories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Ondansetron

    go.drugbank.com/drugs/DB00904
    ApprovedInvestigationalWithdrawn

    A competitive serotonin type 3 receptor antagonist. … Commonly formulated as oral tablets, orally disintegrating tablets (ODT), and injections, and available as generic products as well, ondansetron continues to see contemporary innovations in its formulation

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: BRYTEROL® TABLETAS X 8 MG, ZOPHRALEN 4 MG/2 ML IV AMPUL, 5 ADET
  6. Drug

    Cyclobenzaprine

    go.drugbank.com/drugs/DB00924
    ApprovedInvestigational

    [A184982] It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from [Amitriptyline] by only a single double bond. … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been available for human use since 1977.

    Synonyms: N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Δ5,γ-propylamine, (3-Dibenzo[a,d]cyclohepten-5-ylidene-propyl)-dimethyl-amineMixtures: DOBRIX ®, Therabenzaprine-90-5
  7. Drug

    Phenoxybenzamine

    go.drugbank.com/drugs/DB00925
    ApprovedInvestigational

    It has been used to treat hypertension and as a peripheral vasodilator.

    Categories: Peripheral alpha-1 blockers, Adrenergic alpha-1 Receptor Antagonists
  8. Drug

    Cycrimine

    go.drugbank.com/drugs/DB00942
    Approved

    Cycrimine is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and management of Parkinson's disease.

    Synonyms: alpha-cyclopentyl-alpha-phenyl-1-piperidinepropanolCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Fexofenadine

    go.drugbank.com/drugs/DB00950
    ApprovedInvestigational

    [L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation … [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a racemic mixture in which both enantiomers display approximately equivalent antihistamine activity.

    Synonyms: 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acidMixtures: ALERMED® D, FEXU D® SUSPENSION
  10. Drug

    Naratriptan

    go.drugbank.com/drugs/DB00952
    Approved

    Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.

    Synonyms: N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide, N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamideCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring