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Sevoflurane
go.drugbank.com/drugs/DB01236ApprovedInvestigationalVet approved[L42340] It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. … Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesSynonyms: 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propaneBromodiphenhydramine
go.drugbank.com/drugs/DB01237ApprovedBromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies.
Synonyms: 2-(p-bromo-α-phenylbenzyloxy)-N,N-dimethylethylamine, β-(p-bromobenzhydryloxy)ethyldimethylamineEpoprostenol
go.drugbank.com/drugs/DB01240ApprovedInvestigationalA prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue.
Categories: Prostaglandins ISynonyms: Prostaglandin X, (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acidDecamethonium
go.drugbank.com/drugs/DB01245ApprovedDecamethonium is used in anesthesia to cause paralysis. It is a short acting depolarizing muscle relaxant. … It is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor.
Synonyms: N,N,N,N',N',N'-hexamethyl-1,10-decanediaminiumGliquidone
go.drugbank.com/drugs/DB01251ApprovedGliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. … This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesCarbetocin
go.drugbank.com/drugs/DB01282ApprovedInvestigationalCarbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. … It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
Synonyms: 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin, 1-butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocinProducts: KARPAVER 100 MCG/1 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET, KARPAVER 100 MCG/1 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 5 ADETLumiracoxib
go.drugbank.com/drugs/DB01283ApprovedWithdrawnLumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID).
Categories: COX-2 Inhibitors, Cytochrome P-450 SubstratesSynonyms: 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acidFenoterol
go.drugbank.com/drugs/DB01288ApprovedWithdrawnFenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.
Synonyms: 1-(p-hydroxyphenyl)-2-((β-hydroxy-β-(3',5'-dihydroxyphenyl))ethyl)aminopropane, 5-{1-Hydroxy-2-[2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-benzene-1,3-diolInternational brands: Berotec NOxtriphylline
go.drugbank.com/drugs/DB01303ApprovedIt is marketed under the name Choledyl SA, and several forms of oxytriphylline have been discontinued. In the US, oxtriphylline is no longer available. … Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: Choledyl Sa Tablets 600mg, Choledyl Sa Tablets 400mgQuinethazone
go.drugbank.com/drugs/DB01325ApprovedQuinethazone, marketed as Hydromox, is a thiazide diuretic indicated for hypertension. Patients may experience adverse reactions such as dizziness, dry mouth, nausea, and hypokalemia.
Categories: Heterocyclic Compounds, 2-Ring